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Quick Comparison of Lenovo ThinkSystem SR650 V2 Server vs HPE ProLiant DL380 Gen10 Plus Server at a Glance

The server comparison table provides a quick overview of the key specifications and key features for Lenovo ThinkSystem SR650 V2 Server and HPE ProLiant DL380 Gen10 Plus Server Let’s take a look at the comparison table below.

Features
Lenovo ThinkSystem SR650 V2 Server

Lenovo ThinkSystem SR650 V2 Server

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HPE ProLiant DL380 Gen10 Plus Server

HPE ProLiant DL380 Gen10 Plus Server

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Server Type / Form Factor

  • Type: Rack Server

  • Form Factor: 2U Rackmount

  • Socket: Dual socket (supports up to two 3rd Gen Intel Xeon Scalable processors, up to 40 cores/socket)

  • Type: Rack Server

  • Form Factor: 2U Rackmount

  • Socket: Dual socket (supports up to 2 processors)
Processor (CPU)

  • Supported CPUs: Up to two 3rd Generation Intel Xeon Scalable processors (up to 40 cores per socket, 270 W TDP)

  • Processor Family: 3rd Generation Intel Xeon Scalable Processors

  • Supported Cores: 8 to 60 cores per CPU (e.g. Xeon Gold 6326, 6330N, 8352, 8380)

  • Base Frequency: ~2.1 GHz to ~3.6 GHz depending on model

  • Max TDP: ~105 W to 270 W per processor
Memory (RAM)

  • Memory Type: TruDDR4 RDIMM / 3DS RDIMM ECC

  • DIMM Slots: Up to 32 slots total (16 per CPU)

  • Max Capacity: Up to 8 TB system memory (using 256 GB 3DS RDIMMs); up to 12 TB with persistent memory

  • Speed: Up to 3200 MT/s

  • Type: DDR4 HPE SmartMemory (RDIMM/LRDIMM and Intel Optane Persistent Memory)

  • DIMM Slots: 32 (16 per processor)

  • Max Capacity: Up to 8.1 TB using RDIMM/LRDIMM, or up to 11.2 TB with Intel Optane Persistent Memory

  • Speed: Up to 3200 MT/s (depending on CPU and memory type)
Storage

  • Drive Bay Options:

    • Front: up to 24 × 2.5 or 12 × 3.5 hot swap drives

    • Middle: up to 8 × 2.5 or 4 × 3.5 hot swap bays

    • Rear: up to 8 × 2.5 or 4 × 3.5 hot swap bays, plus two 7 mm boot drives



  • Boot Options: 2 × internal M.2 SATA/NVMe drives in RAID

  • Controllers: Onboard Intel VROC for SATA/NVMe; optional hardware RAID/HBA adapters

  • Front Drive Bays: Multiple chassis options:

    • 8SFF standard (expandable to 24SFF)

    • 8LFF standard (expandable to 12LFF)



  • Rear/Mid Tray Options: Optional 6SFF rear, 8SFF mid tray, LFF mid tray

  • Supported Drive Types: SAS, SATA, NVMe (U.2/U.3 with tri-mode controllers)

  • M.2 Boot: Optional M.2 SATA boot or NVMe boot support
Expansion / Connectivity

  • PCIe Slots: Up to eight PCIe Gen 4 slots (all rear accessible) plus one OCP 3.0 mezzanine slot;

  • GPU Support: Supports up to eight single width GPUs or three double width GPUs

  • Networking: Embedded LOM + optional OCP adapter for 1/10/25 GbE

  • PCIe Slots: Up to 9 expansion slots (PCIe Gen4) depending on riser configuration

  • OCP Networking: 1× OCP 3.0 x16 mezzanine slot (flexible networking/storage)
Redundancy & Reliability

  • Power Supplies: Dual hot plug redundant PSUs ranging from 750 W to 1800 W (Platinum/Titanium, AC or DC options)

  • Cooling: Air cooled with up to six hot swap fans and N+1 redundancy

  • Power Supplies: Redundant hot-plug Flex Slot Platinum power (e.g., 800W)

  • Cooling: Standard fans; high performance fan option required for NVMe or GPU configs
Operating System Support

  • Microsoft Windows Server

  • Red Hat Enterprise Linux

  • SUSE Linux Enterprise Server

  • VMware ESXi

  • Canonical Ubuntu Server LTS

  • Microsoft Windows Server 2019 / 2022

  • Red Hat Enterprise Linux (RHEL)

  • SUSE Linux Enterprise Server (SLES)

  • VMware ESXi (7.x / 8.x)

  • Other: Ubuntu, Oracle Linux, Citrix XenServer
Security Features

  • Lenovo XClarity Controller with Platform Firmware Resiliency (PFR)

  • Embedded TPM 2.0 (FIPS/CC TCG certified)

  • Optional lockable bezel and chassis intrusion detection

  • Silicon Root of Trust: Secures firmware and processor identity at ROM-level

  • Secure Boot & Erase: Ensures verified, tamper resistant system startup and clean decommission

  • iLO 5 Security Enhancements: Server Configuration Lock, iLO Security Dashboard, BIOS advisor
Management & Monitoring

  • Lenovo XClarity Controller (XCC) with RESTful Redfish API

  • Supports Lenovo XClarity Administrator, Energy Manager, and integrations with VMware, Microsoft System Center

  • iLO 5: Embedded management for remote control, firmware updates, monitoring

  • Tools: HPE InfoSight (predictive analytics), OneView, Intelligent Provisioning

  • APIs: Redfish, RESTful, SNMP v3, IPMI 2.0
Warranty & Support

  • Standard Warranty: 3 Years Warranty

  • Support Options: Warranty extensions available via Lenovo service plans

  • Standard Warranty: 3 Years Parts, 3 Years Labor, 3 Years Onsite (Next Business Day)

  • Optional Services: HPE Pointnext Tech Care, Foundation Care, Proactive Care

Key Features Comparison

High Processing Power
Equipped with Intel Xeon Scalable processors (up to 3rd Gen), the SR650 V2 delivers exceptional performance for demanding applications
Massive Storage Capacity
With support for up to 40 drives, the server offers extensive storage options, providing flexibility for large data volumes
Enhanced Memory Capacity
Featuring up to 8TB of DDR4 memory, the SR650 V2 allows for seamless multitasking and efficient processing of complex applications
Energy Efficiency
Built to reduce power consumption, Lenovo’s energy-efficient architecture helps minimize operational costs while delivering high performance
Advanced Virtualization Capabilities
Designed to support virtualized workloads, the SR650 V2 helps enterprises maximize their infrastructure efficiency and manage multiple virtual machines
Flexible Networking Options
With support for multiple networking configurations, including 10/25 GbE, the SR650 V2 enables high-speed connectivity and robust network performance
High Performance for Intensive Workloads
Powered by 3rd Gen Intel® Xeon® Scalable Processors, the DL380 Gen10 Plus delivers exceptional performance, making it ideal for data-intensive applications.
Scalable Storage Solutions
Offers flexible storage options, from SATA and SAS HDDs to high-speed NVMe SSDs, providing businesses with the storage configurations they need.
Advanced Security Features
Built with HPE Silicon Root of Trust, a robust security framework that ensures secure boot and protects against unauthorized firmware modifications.
Flexible Expansion and Connectivity
The DL380 Gen10 Plus supports PCIe Gen4, enabling high-speed expansion for enhanced networking and storage capabilities.
Energy Efficient
Designed for lower power consumption without sacrificing performance, reducing operational costs and supporting eco-friendly initiatives.
Redundant Power Supplies and Cooling
Ensures reliability with dual power supplies and optimized cooling, minimizing downtime and maximizing productivity.

Lenovo ThinkSystem SR650 V2 Server vs HPE ProLiant DL380 Gen10 Plus Server : Which should I choose?

Choosing the right server is a critical decision for any business, and comparing Lenovo ThinkSystem SR650 V2 Server and HPE ProLiant DL380 Gen10 Plus Server gives you clear insights into which solution aligns best with your IT requirements. These servers are built for high performance, but they may differ in areas such as processor capacity, memory, storage, and scalability, making a side-by-side comparison easy.

This direct comparison helps you quickly identify the strengths and limitations of each server, which helps you determine which model best supports your workloads, applications, and long-term IT goals. By evaluating them together, you can make a smarter investment that ensures reliability and efficiency for your business.

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