Quick Comparison of HPE ProLiant ML350 Gen10 Server vs Lenovo ThinkSystem ST550 Tower Server at a Glance

The server comparison table provides a quick overview of the key specifications and key features for HPE ProLiant ML350 Gen10 Server and Lenovo ThinkSystem ST550 Tower Server Let’s take a look at the comparison table below.

Features	HPE ProLiant ML350 Gen10 Server View Check the Price	Lenovo ThinkSystem ST550 Tower Server View Check the Price
Server Type / Form Factor	Type: Tower Server (convertible to rack mount with optional kit) Form Factor: 4U chassis (rackable takes up ~5U) Socket: Dual socket (supports up to 2 Intel Xeon Scalable CPUs)	Type: Tower Server Form Factor: 4U rackable tower Socket: Dual socket (supports 2nd Gen Intel Xeon Scalable Platinum/Silver up to 125 W per CPU)
Processor (CPU)	Processor Family: Intel Xeon Scalable Processors (1st or 2nd Gen) Supported Cores per CPU: 6 to 28 cores (e.g., Xeon Bronze to Platinum models) L3 Cache: Up to 38.5 MB per processor Max Frequency: Up to ~3.5 3.9 GHz depending on CPU model Max TDP: Up to 205 W	Supported CPUs: Up to two 2nd Generation Intel Xeon Scalable processors (Platinum/Silver up to 125 W)
Memory (RAM)	Type: HPE DDR4 SmartMemory (RDIMM, LRDIMM, or Intel Optane DC Persistent Memory) DIMM Slots: 24 (12 per processor) Maximum Capacity: Up to 3 TB using 128 GB DIMMs (RDIMM/LRDIMM) Speed: 2666 or 2933 MT/s depending on CPU generation Memory Protection: Advanced ECC, Memory Lock step, Online Spare	Memory Type: TruDDR4 ECC Registered DIMM Slots: 12 slots total (6 per CPU) Max Capacity: Up to 768 GB with 64 GB DIMMs Speed: Up to 2933 MT/s (2666 MT/s also supported)
Storage	Front Drive Bays: Up to 12 × LFF (3.5") SAS/SATA hot plug Or up to 24 × SFF (2.5") SAS/SATA/NVMe hot plug Expansion Options: Additional bay trays may support NVMe or hybrid drive layouts RAID Controllers: HPE Smart Array P408i a SR, P816i a SR, E208i a, P824i p, etc. Boot Options: Optional M.2 boot module or Smart Array controller-based boot	Drive Bay Options: Up to 16 × 2.5 SAS/SATA hot swap bays (including up to 4 NVMe) Or up to 8 × 3.5 hot swap bays Plus up to 4 × 2.5 internal bays + 2 × M.2 boot drives Controllers: Software RAID standard; optional hardware RAID and up to 16 port HBAs available
Expansion / Connectivity	PCIe Slots: Up to 8 PCIe 3.0 slots in tower chassis for GPU, networking or HBA Networking: Embedded 4 × 1 GbE NIC; optional Flexible LOM (OCP-style mezzanine) available	PCIe Slots: Up to 6 × PCIe 3.0 slots (with 2 CPUs installed) Networking: 2 × 1 GbE LOM standard; optional NICs via PCIe
Redundancy & Reliability	Power Supplies: Standard 500 W or 800 W non hot plug PSU; optional redundant 500 W or 800 W Flex Slot PSUs Cooling: Standard 4 fans; optional redundant fan cage for GPU or NVMe heavy configs Security Features: TPM 2.0 module support, iLO Secure Boot, chassis padlock and bezel lock	Power Supplies: 1 × fixed 450 W Gold PSU; or 2 × hot swap redundant PSUs (550 W/750 W/1100 W Platinum, or 750 W Titanium) Cooling: Hot swap chassis fans, chassis intrusion switch; drive/tray redundancy
Operating System Support	Microsoft Windows Server 2016 / 2019 / 2022 Red Hat Enterprise Linux (RHEL) SUSE Linux Enterprise Server (SLES) VMware ESXi (vSphere 6.7 U3, 7.x, 8.x) Other: Ubuntu, Oracle Linux, Citrix XenServer	Microsoft Windows Server Red Hat Enterprise Linux SUSE Linux Enterprise Server VMware vSphere / ESXi
Security Features	Silicon Secured Boot: iLO 5 system configuration lock, BIOS advisor, secure recovery Encryption: TPM 2.0 support, secure erase, firmware rollback, AES/3DES encryption	Lenovo ThinkShield (lockable bezel, Kensington lock slot, chassis intrusion) TPM 1.2 and TPM 2.0 supported Predictive Failure Analysis, hot swap redundant drives and PSUs
Management & Monitoring	Integrated Lights Out (iLO 5): Full remote console, firmware updates, health monitoring Management Tools: HPE Intelligent Provisioning, OneView, InfoSight API Support: Redfish, RESTful, IPMI 2.0, SNMP v3	Lenovo XClarity Controller (embedded) with XClarity Administrator support Includes Redfish API support and XClarity Integrator and Energy Manager plugins
Warranty & Support	Standard Warranty: 3 Year Parts, 3 Year Labor, 3 Year Onsite (Next Business Day) Optional Services: HPE Foundation Care, Proactive Care, Pointnext Tech Care	Standard Warranty: 3 Years Warranty Support Options: Warranty extensions available via Lenovo service offerings

Key Features Comparison

Powerful Scalability:

Powered by Intel® Xeon® Scalable processors, the ML350 Gen10 offers robust, enterprise-level performance, making it an ideal choice for organizations with growing data needs.

Flexible Expansion Options:

Supports a broad range of storage configurations, from SATA HDDs to high-speed NVMe SSDs, with the capability to add up to 24 drive bays and 12 DIMM slots for versatile storage and memory expansion.

Enhanced Security and Reliability:

Features HPE’s Silicon Root of Trust technology to safeguard firmware against threats, along with robust redundancy features like dual power supplies to minimize downtime.

Advanced Management with HPE iLO 5:

HPE Integrated Lights-Out (iLO 5) simplifies server management with remote monitoring and diagnostic tools, making it easier to maintain and secure your IT infrastructure.

Energy Efficient Design:

Optimized for low power consumption, the ML350 Gen10 helps reduce operational costs, making it a cost-effective solution for high-performance needs.

Tower or Rack Mount Flexibility:

With the ability to be configured as a tower or rack-mount server, it’s adaptable to various deployment environments, from data centers to office setups.

High Performance and Scalability

The ST550 supports Intel Xeon Scalable processors and provides flexible storage options, making it suitable for demanding applications and workloads as your business grows.

Advanced Storage Flexibility

With support for multiple storage configurations, including up to 12 3.5-inch drives, businesses can scale their storage capacity as needed

Enhanced Virtualization Support

Optimized for virtualization workloads, the ST550 offers significant performance enhancements for running virtualized environments, increasing operational efficiency

Energy-Efficient Design

Lenovo’s energy-efficient architecture ensures the ST550 delivers performance without excessive power consumption, helping to reduce operational costs

Remote Management Capabilities

Integrated with Lenovo XClarity Controller for remote management, providing streamlined deployment and proactive monitoring, even in remote or distributed environments

Security Features

Built-in security features, including TPM 2.0 and secure boot, protect your sensitive data and ensure the integrity of your server

HPE ProLiant ML350 Gen10 Server vs Lenovo ThinkSystem ST550 Tower Server : Which should I choose?

Choosing the right server is a critical decision for any business, and comparing HPE ProLiant ML350 Gen10 Server and Lenovo ThinkSystem ST550 Tower Server gives you clear insights into which solution aligns best with your IT requirements. These servers are built for high performance, but they may differ in areas such as processor capacity, memory, storage, and scalability, making a side-by-side comparison easy.

This direct comparison helps you quickly identify the strengths and limitations of each server, which helps you determine which model best supports your workloads, applications, and long-term IT goals. By evaluating them together, you can make a smarter investment that ensures reliability and efficiency for your business.

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