Quick Comparison of HPE ProLiant ML110 Gen10 Server vs Lenovo ThinkSystem SR250 V2 Server at a Glance

The server comparison table provides a quick overview of the key specifications and key features for HPE ProLiant ML110 Gen10 Server and Lenovo ThinkSystem SR250 V2 Server Let’s take a look at the comparison table below.

Features	HPE ProLiant ML110 Gen10 Server View Check the Price	Lenovo ThinkSystem SR250 V2 Server View Check the Price
Server Type / Form Factor	Type: Tower Server (upgradeable to rack mount with optional kit) Form Factor: 4.5U Tower Socket: Single socket (supports 1 Intel Xeon Scalable CPU)	Type: Rack Server Form Factor: 1U Rackmount Socket: Single socket (Intel Xeon E 2300 series up to 8 cores; or Intel Pentium G series up to 2 cores)
Processor (CPU)	Processor Family: Intel Xeon Scalable (1st and 2nd Generation) Core Options: 4, 6, 8 or up to 14 cores (e.g. Xeon Silver 4210, 4210R, Gold 5222) Max Frequency: Up to ~3.6 GHz Max TDP: Up to ~110 W Memory Capacity (per socket): Up to 192 GB with 6 × 32 GB RDIMM	Supported CPUs: One Intel Xeon E 2300 series processor (up to 8 cores, 95 W max) Also supports: Intel Pentium G6405, G6505, G6605 processors (2 cores)
Memory (RAM)	Type: DDR4 HPE SmartMemory (RDIMM only) DIMM Slots: 6 slots (1 DIMM per channel across 6 memory channels) Max Capacity: 192 GB (6 × 32 GB at 2933 MT/s for Gen2 CPUs) Speed: Up to 2933 MT/s (depending on CPU model)	Memory Type: TruDDR4 ECC UDIMM DIMM Slots: 4 slots total Max Capacity: Up to 128 GB (4×32 GB UDIMM at 3200 MT/s) Speed: 3200 MT/s (Xeon) or 2666 MT/s (Pentium)
Storage	Drive Bays: Up to 8 × LFF (hot plug SATA/SAS) or 16 × SFF (hot plug) Controller: HPE Smart Array S100i SR Gen10 (software RAID), or optional P408i p, E208i p HW controllers Boot Options: Optional M.2 module or SATA/eMMC boot (UEFI only)	Drive Bay Options: Up to 10 × 2.5 hot swap SAS/SATA drives Up to 8 × 2.5 hot swap SAS/SATA drives Up to 4 × 3.5 hot swap SATA/SAS drives Mixed: 3× 3.5 SATA + 1× 3.5 NVMe Boot Option: Optional SATA mirrored M.2 drive via PCIe adapter RAID: Intel VROC software RAID or optional hardware RAID configs
Expansion / Connectivity	PCIe Slots: 5 × PCIe 3.0 slots (mix of x16 and x8 slots) Networking: Embedded dual-port 1 GbE (Intel 332i); optional FlexibleLOM mezzanine for higher-throughput NICs	PCIe Slots: Config dependent: 2× PCIe Gen 4 ×8, or 1× PCIe Gen 4 ×16; internal RAID slot PCIe Gen4 ×8 (×4 interface) Networking: Embedded dual 1 GbE LOM (Broadcom BCM5720) plus one dedicated GbE for XCC management
Redundancy & Reliability	Power Supply: 350 W or 550 W ATX PSUs; optional 800 W Flex Slot hot plug PSU Cooling: Standard 2 non hot plug fans; optional redundant fan kit recommended for high RPM drives or SAS SSDs Security: Silicon Root of Trust, UEFI Secure Boot, Secure Recovery, Runtime Firmware Validation	Power Supplies: Supports single fixed PSU or redundant pair of hot swap 450 W power supplies Cooling: Air cooled chassis with standard thermal design
Operating System Support	Microsoft Windows Server 2016 / 2019 / 2022 Red Hat Enterprise Linux (RHEL) SUSE Linux Enterprise Server (SLES) VMware ESXi (vSphere 6.7 U3, 7.x, 8.x) ClearOS, CentOS, Ubuntu, Oracle Linux	Microsoft Windows Server 2022 Red Hat Enterprise Linux 8.4 or later SUSE Linux Enterprise Server 15 SP3 or later VMware ESXi 7.0 U3 or later
Security Features	iLO 5 Security: Configurable server lock, BIOS Advisor, security dashboard TPM 2.0 Support: Optional FIO module Firmware Security: Secure Boot, Firmware rollback, Runtime Validation	Lenovo XClarity Controller (management engine) Embedded TPM 2.0 Optional front lockable security bezel
Management & Monitoring	Embedded: HPE iLO Standard with Intelligent Provisioning Optional Licenses: iLO Advanced, iLO Advanced Premium Security Edition Tools: Active Health System, iLO RESTful API, OneView Standard, iLO Amplifier Pack	Lenovo XClarity Controller with XClarity Administrator support RESTful API and centralized management via XClarity suite
Warranty & Support	Standard: 3 Year Parts, 3 Year Labor, 3 Year Onsite (Next Business Day) Service Options: HPE Pointnext Tech Care, Foundation Care, Proactive Care	Standard Warranty: 3 Year warranty Support Options: Warranty extensions available via Lenovo service offerings

Key Features Comparison

Cost-Effective Performance

Powered by Intel® Xeon® Scalable processors, the ML110 Gen10 provides enterprise-grade performance at a budget-friendly price, making it an excellent choice for small to medium businesses.

Compact Tower Design

Its compact, quiet tower design is ideal for small offices and remote branch environments, saving valuable space without compromising performance.

Flexible Storage Options

Supports up to 8 LFF (Large Form Factor) or 16 SFF (Small Form Factor) drive bays, enabling businesses to choose storage configurations that suit their workloads, from HDDs to SSDs.

Enhanced Security Features

Equipped with HPE’s Silicon Root of Trust, protecting your server against firmware-level threats and ensuring data integrity across operations.

Energy Efficient and Quiet Operation

Designed to reduce power consumption and operate quietly, making it ideal for in-office deployments where energy efficiency and low noise are essential.

Simplified Management with HPE iLO 5

HPE’s Integrated Lights-Out (iLO) 5 provides easy remote management, streamlining server maintenance, monitoring, and security for IT administrators.

Cost-Effective Performance

Provides an excellent balance of price and performance, ideal for businesses looking for an affordable solution without compromising capabilities

High Processing Power

Compact 1U Design

Space-saving form factor suitable for small data centers or offices, maximizing space utilization

Flexible Storage Options

Offers a range of storage options, from SATA HDDs to NVMe SSDs, to match different data storage needs

Enhanced Security

Lenovo’s ThinkShield security suite protects your data and infrastructure from threats

Energy Efficient

Low power consumption helps businesses reduce operational costs while remaining eco-friendly

HPE ProLiant ML110 Gen10 Server vs Lenovo ThinkSystem SR250 V2 Server : Which should I choose?

Choosing the right server is a critical decision for any business, and comparing HPE ProLiant ML110 Gen10 Server and Lenovo ThinkSystem SR250 V2 Server gives you clear insights into which solution aligns best with your IT requirements. These servers are built for high performance, but they may differ in areas such as processor capacity, memory, storage, and scalability, making a side-by-side comparison easy.

This direct comparison helps you quickly identify the strengths and limitations of each server, which helps you determine which model best supports your workloads, applications, and long-term IT goals. By evaluating them together, you can make a smarter investment that ensures reliability and efficiency for your business.

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