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Quick Comparison of HPE ProLiant DL385 Gen11 Server vs Lenovo ThinkSystem SR650 V3 Server at a Glance

The server comparison table provides a quick overview of the key specifications and key features for HPE ProLiant DL385 Gen11 Server and Lenovo ThinkSystem SR650 V3 Server Let’s take a look at the comparison table below.

Features
HPE ProLiant DL385 Gen11 Server

HPE ProLiant DL385 Gen11 Server

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Lenovo ThinkSystem SR650 V3 Server

Lenovo ThinkSystem SR650 V3 Server

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Server Type / Form Factor

  • Type: Rack Server

  • Form Factor: 2U Rackmount

  • Socket: Dual-socket (supports up to 2 processors)

  • Type: Rack Server

  • Form Factor: 2U Rackmount

  • Socket: Dual socket (supports 4th or 5th Gen Intel Xeon Scalable up to 64 cores/socket)
Processor (CPU)

  • Processor Family: AMD EPYC™ 9004 Series

  • Max Supported: Up to AMD EPYC 9654 (96 cores, 192 threads)

  • Architecture: 5nm, Zen 4

  • Max TDP: Up to 400W per processor

  • Supported CPUs: Up to two 5th Gen Intel Xeon Scalable (up to 64 cores/thread per socket, TDP up to 350 W)

  • Also supports: 4th Gen Xeon Scalable (up to 60 cores/socket, 350 W TDP)
Memory (RAM)

  • Type: DDR5 Registered DIMMs (RDIMMs)

  • DIMM Slots: 24 (12 per CPU)

  • Max Capacity: Up to 6TB

  • Speed: Up to 5600 MT/s

  • Protection: ECC, Mirroring, Fast Failover

  • Memory Type: DDR5 RDIMM (TruDDR5) ECC

  • DIMM Slots: Up to 32 DIMM slots (16 per CPU)

  • Max Capacity: Up to 8 TB using 256 GB 3DS RDIMMs

  • Speed: Up to 5600 MT/s (5th Gen) or 4800 MT/s (4th Gen)
Storage

  • Drive Bays: Up to 12x LFF or 24x SFF (front)

  • Rear Drives: Optional 2x SFF or NVMe

  • Supported Types: SAS, SATA, NVMe

  • RAID: HPE Smart Array (RAID 0, 1, 5, 6, 10, 50, 60)

  • Max Capacity: Over 400TB (based on configuration)

  • Drive Bay Options:

    • Front: up to 12 × 3.5 or 24 × 2.5 hot swap bays

    • Middle: up to 4 × 3.5 or 8 × 2.5 hot swap bays

    • Rear: up to 4 × 3.5 or 8 × 2.5 hot swap, plus optional 2 × 7 mm boot bays



  • Boot Options: Internal 2 × M.2 SATA/NVMe drives in RAID

  • Controllers: Supports VROC/VMD, onboard SW RAID; optional hardware RAID/HBA adapters
Expansion / Connectivity

  • PCIe Slots: Up to 8x PCIe Gen5

  • Networking: OCP 3.0 Slot (1/10/25/100GbE options)

  • GPU Support: Up to 4x Single-width or 3x Double-width GPUs

  • PCIe Slots: Up to 12 PCIe Gen 4/5 slots plus 1 × OCP 3.0 mezzanine slot; up to 10 rear accessible PCIe slots

  • GPU Support: Up to 8 single-width GPUs or 3 double-width GPUs

  • Networking: LOM via OCP 3.0 slot or optional NIC adapters
Redundancy & Reliability

  • Power: Redundant Hot-Plug Power Supplies (800W–2400W)

  • Cooling: Redundant Hot-Plug Fans

  • Drive Redundancy: RAID support

  • Firmware Security: HPE Silicon Root of Trust

  • Power Supplies: Dual hot plug redundant PSUs: 750 W – 2600 W, Platinum/Titanium (AC & DC options)

  • Cooling: Air cooled with N+1 hot swap fans (5 6 depending on config), supports performance and standard fan types
Operating System Support

  • Microsoft Windows Server

  • Red Hat Enterprise Linux (RHEL)

  • SUSE Linux Enterprise Server (SLES)

  • VMware ESXi

  • Ubuntu, Oracle Linux, ClearOS

  • Microsoft Windows Server including 2022

  • Red Hat Enterprise Linux 8.x/9.x

  • SUSE Linux Enterprise Server 15 SP4/SP5+ or later

  • VMware ESXi including 7.0 U3 or later
Security Features

  • Silicon Root of Trust

  • Secure Boot & Secure Erase

  • TPM 2.0 (FIPS-certified optional)

  • Firmware Verification & Intrusion Detection

  • Lenovo XClarity Controller 2 (service processor)

  • Embedded TPM 2.0 with PFR (Platform Firmware Resiliency); chassis intrusion, administrator password security

  • Optional lockable bezel available
Management & Monitoring

  • iLO 6: Integrated Lights-Out Management

  • Tools: HPE OneView, InfoSight, Redfish API

  • Remote Access: Firmware Updates, Monitoring, Alerting

  • Lenovo XClarity Controller (XCC2) with remote KVM over dedicated port

  • Integration via XClarity Administrator, Energy Manager, REST API support
Warranty & Support

  • Warranty: 3-Year Parts, 3-Year Labor, 3-Year Onsite (Next Business Day)

  • Optional Support: HPE Pointnext, Foundation Care, Proactive Care

  • Standard Warranty: 3 Year Customer Replaceable Unit & Onsite Service

  • Optional Upgrades: 4 hour, 2 hour response, or extended up to 5 year coverage via Lenovo Services

Key Features Comparison

Enhanced Performance
Powered by the latest AMD EPYC™ 9004 Series processors, the HPE ProLiant DL385 Gen11 delivers superior performance and high-speed processing to handle even the most data-intensive applications.
Scalable Storage and Memory
Offers flexible storage options, supporting up to 184TB, and up to 8TB of DDR5 memory, enabling efficient handling of high-performance workloads, virtualization, and large databases.
Advanced Security Features
The server supports a variety of storage systems, including NVMe SSDs and SAS/SATA HDDs, so you can tailor your storage solution to meet your specific needs From fast data traffic up to ample storage the DL385 Gen11 offers the flexibility you need.
Virtualization and Cloud-Ready
Ideal for virtualized environments, this server supports software-defined infrastructures and is optimized for cloud deployments, making it a great choice for enterprises looking to streamline their digital transformation.
Energy Efficiency
Engineered for energy efficiency, the DL385 Gen11 minimizes power usage, helping businesses reduce operating costs while aligning with environmental goals.
High I/O Capacity
With support for PCIe Gen5, the server delivers higher data throughput and faster connectivity options, allowing faster processing and data transfer rates.
High Performance and Scalability
Equipped with the latest Intel Xeon Scalable processors and up to 8TB of memory, making it ideal for demanding applications and heavy workloads
Flexible Storage Options
Supports a range of storage configurations, including NVMe, SSD, and HDD options, to optimize storage performance and capacity for your needs
Enhanced Security and Reliability
Built-in ThinkShield security and TPM options protect your data, while Lenovo’s Trusted Platform provides peace of mind against threats
Energy Efficiency and Cost Savings
Advanced cooling technology and energy-efficient components reduce power consumption, providing cost savings for data centers
Virtualization-Ready
Ideal for virtualization with support for multiple hypervisors, enabling optimized resource utilization and operational efficiency
Flexible Expansion Capabilities
High I/O flexibility with multiple PCIe slots allows easy scaling to meet future business needs

HPE ProLiant DL385 Gen11 Server vs Lenovo ThinkSystem SR650 V3 Server : Which should I choose?

Choosing the right server is a critical decision for any business, and comparing HPE ProLiant DL385 Gen11 Server and Lenovo ThinkSystem SR650 V3 Server gives you clear insights into which solution aligns best with your IT requirements. These servers are built for high performance, but they may differ in areas such as processor capacity, memory, storage, and scalability, making a side-by-side comparison easy.

This direct comparison helps you quickly identify the strengths and limitations of each server, which helps you determine which model best supports your workloads, applications, and long-term IT goals. By evaluating them together, you can make a smarter investment that ensures reliability and efficiency for your business.

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