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Quick Comparison of HPE ProLiant DL380 Gen10 Server vs Dell PowerEdge R750xs Rack Server at a Glance

The server comparison table provides a quick overview of the key specifications and key features for HPE ProLiant DL380 Gen10 Server and Dell PowerEdge R750xs Rack Server Let’s take a look at the comparison table below.

Features
HPE ProLiant DL380 Gen10 Server

HPE ProLiant DL380 Gen10 Server

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Dell PowerEdge R750xs Rack Server

Dell PowerEdge R750xs Rack Server

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Server Type / Form Factor

  • Type: Rack Server

  • Form Factor: 2U Rackmount

  • Socket: Dual socket (supports up to 2 processors)

  • Type: Rack Server

  • Form Factor: 2U Rackmount

  • Socket: Dual socket (supports up to 3rd Generation Intel Xeon Scalable, up to 32 cores/socket)
Processor (CPU)

  • Processor Family: Intel Xeon Scalable Processors (1st and 2nd Gen)

  • Supported Cores: 4 to 28 cores per CPU (e.g. Bronze 3200, Silver 4200, Gold 5200/6200 series)

  • Base Frequency: ~1.9 GHz to ~3.2 GHz depending on model

  • Max TDP: ~85 W to ~205 W per processor

  • Memory per Socket: Up to 1 TB (Silver/Gold) or up to 4.5 TB per socket (Large memory tiers with Optane)

  • Supported CPUs: Up to two 3rd Generation Intel Xeon Scalable processors (up to 32 cores per socket)

  • Max TDP: ~220 W per processor
Memory (RAM)

  • Type: DDR4 HPE SmartMemory (RDIMM, LRDIMM, DC Persistent Memory)

  • DIMM Slots: 24 slots (12 per processor, 6 channels each)

  • Max Capacity:

    • Up to 2.0 TB using RDIMM @ 2933 MT/s

    • Up to 3.0 TB using LRDIMM @ 2933 or 3200 MT/s

    • Up to 4.5 TB per socket using Intel Optane Persistent Memory (select SKUs)

  • Memory Type: DDR4 Registered ECC (RDIMM)

  • DIMM Slots: 16 slots total (8 per CPU)

  • Max Capacity: Up to 1 TB

  • Speed: Up to 3200 MT/s
Storage

  • Front Drive Bays: Flexible chassis options:

    • Up to 12 × LFF (3.5") SAS/SATA HDD/SSD

    • Or up to 24 × SFF (2.5") SAS/SATA/NVMe



  • Optional Rear/Mid-Tray: Additional 2–6 SFF or LFF drives

  • Supported Drive Types: SAS, SATA, NVMe U.2/U.3 via tri mode Smart Array controllers

  • Boot Options: Optional M.2 SATA boot module

  • Drive Bay Options:

    • Up to 8 × 3.5 SAS/SATA

    • Up to 12 × 3.5 SAS/SATA

    • Up to 8 × 2.5 SAS/SATA/NVMe

    • Up to 16 × 2.5 SAS/SATA + 8 × NVMe



  • Rear Bays: Up to 2 × 2.5 SAS/SATA/NVMe

  • Controllers: PERC H345, H355, H745, H755, H755N; HBA355i; S150; Boot: BOSSS1 dual M.2; External: PERC H840
Expansion / Connectivity

  • PCIe Slots: Up to 8–9 × PCIe 3.0 slots depending on riser configuration

  • Networking: OCP 3.0 mezzanine slot available (for 10/25/100 GbE modules)

  • PCIe Slots: Up to 5 PCIe Gen 4 + 1 Gen 3 riser slots (depending on configuration)

  • Networking: Embedded dual 1 GbE LOM; optional OCP 3.0 mezzanine card
Redundancy & Reliability

  • Power Supplies: Redundant Flex Slot power supplies (e.g., 800 W, 1600 W Platinum)

  • Cooling: Hot-plug fans; high-performance kit required for NVMe, GPU or high-TDP CPU setups

  • RAID Controllers: HPE Smart Array P408i-a SR (Gen10) and other Gen10 tri mode controllers

  • Power Supplies: Hot plug redundant PSUs: 600 W, 800 W, 1100 W, 1400 W (Titanium/Platinum AC or DC options)

  • Cooling: Up to 6 hot swap fans; standard or high performance fan configurations
Operating System Support

  • Microsoft Windows Server 2016 / 2019 / 2022

  • Red Hat Enterprise Linux (RHEL)

  • SUSE Linux Enterprise Server (SLES)

  • VMware ESXi (vSphere 6.7 U3, 7.x, 8.x)

  • Additional: Ubuntu, Oracle Linux, Citrix XenServer

  • Microsoft Windows Server with Hyper V

  • Red Hat Enterprise Linux

  • SUSE Linux Enterprise Server

  • VMware ESXi / vSAN

  • Canonical Ubuntu Server LTS
Security Features

  • iLO 5 Security: Server Configuration Lock, BIOS Advisor, iLO Security Dashboard

  • Secure Boot & Secure Erase: Supported via system firmware

  • TPM 2.0 Support: Optional module available

  • Cryptographically signed firmware; Silicon Root of Trust

  • Secure Boot, Secure Erase, System Lockdown (requires iDRAC9 Enterprise/Datacenter)

  • TPM 2.0 (FIPS/CC TCG certified)
Management & Monitoring

  • Integrated Lights Out (iLO 5): Remote management, firmware control, health alerts

  • Management Tools: HPE Intelligent Provisioning, InfoSight, OneView Standard

  • APIs: Redfish, RESTful API, SNMP v3, IPMI 2.0

  • iDRAC9 with Lifecycle Controller; iDRAC Direct USB port; RESTful Redfish API; iDRAC Service Module

  • Tools: Dell OpenManage Enterprise, CloudIQ; integrations with VMware, Microsoft System Center; Ansible, Terraform support
Warranty & Support

  • Standard Warranty: 3-Year Parts, 3-Year Labor, 3-Year Onsite (Next Business Day)

  • Optional Services: HPE Pointnext Tech Care, Foundation Care, Proactive Care

  • Standard Warranty: 3 Year Dell Basic Hardware Warranty with Next Business Day Onsite Service

  • Optional Extended Support: Dell ProSupport or ProSupport Plus available beyond 3 years

Key Features Comparison

Powerful Performance for Diverse Workloads:
Equipped with Intel® Xeon® Scalable processors, the DL380 Gen10 delivers reliable, high-performance processing for various business applications.
Versatile Storage Options:
Supports a range of storage configurations, from SATA and SAS to ultra-fast NVMe drives, providing flexibility to match your data needs and business growth.
Advanced Security Features
Incorporates HPE’s Silicon Root of Trust technology, offering a secure boot and robust protection against unauthorized firmware changes.
Scalable Architecture and Expansion Flexibility:
With PCIe slots, the DL380 Gen10 offers enhanced flexibility, allowing easy expansion for evolving IT infrastructure and workload demands.
Energy Efficient Design:
Designed to reduce power consumption while maintaining high performance, helping lower operational costs and supporting eco-friendly objectives.
Reliable Redundancy and Fault Tolerance:
Dual power supplies and redundant fans maximize uptime, ensuring continuous operation in mission-critical environments.
Powerful Performance
Powered by the latest Intel Xeon Scalable Processors, the Dell PowerEdge R750xs ensures high-speed performance for demanding applications, handling large datasets and complex tasks with ease
Flexible Storage Options
The R750xs supports a variety of storage configurations, including NVMe, SAS, and SATA drives, allowing you to scale your storage capacity based on your growing business needs.
Enhanced Cooling Efficiency
Featuring multi-vector cooling technology, the R750xs optimizes airflow to maintain efficient thermal management, reducing the risk of overheating and lowering energy consumption.
High Memory Capacity
With support for up to 16 DIMMs and DDR4 or DDR5 memory, the R750xs can handle large-scale data processing, virtualization, and high-performance computing.
Redundant Power Supplies
Equipped with dual hot-plug redundant power supplies, the R750xs ensures continuous uptime, minimizing the risk of system failures during critical operations.

HPE ProLiant DL380 Gen10 Server vs Dell PowerEdge R750xs Rack Server : Which should I choose?

Choosing the right server is a critical decision for any business, and comparing HPE ProLiant DL380 Gen10 Server and Dell PowerEdge R750xs Rack Server gives you clear insights into which solution aligns best with your IT requirements. These servers are built for high performance, but they may differ in areas such as processor capacity, memory, storage, and scalability, making a side-by-side comparison easy.

This direct comparison helps you quickly identify the strengths and limitations of each server, which helps you determine which model best supports your workloads, applications, and long-term IT goals. By evaluating them together, you can make a smarter investment that ensures reliability and efficiency for your business.

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