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Quick Comparison of HPE ProLiant DL380 Gen10 Plus Server vs Dell PowerEdge R750 Rack Server at a Glance

The server comparison table provides a quick overview of the key specifications and key features for HPE ProLiant DL380 Gen10 Plus Server and Dell PowerEdge R750 Rack Server Let’s take a look at the comparison table below.

Features
HPE ProLiant DL380 Gen10 Plus Server

HPE ProLiant DL380 Gen10 Plus Server

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Dell PowerEdge R750 Rack Server

Dell PowerEdge R750 Rack Server

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Server Type / Form Factor

  • Type: Rack Server

  • Form Factor: 2U Rackmount

  • Socket: Dual socket (supports up to 2 processors)

  • Type: Rack Server

  • Form Factor: 2U Rackmount

  • Socket: Dual socket (supports 3rd Generation Intel Xeon Scalable processors, up to 40 cores/socket)
Processor (CPU)

  • Processor Family: 3rd Generation Intel Xeon Scalable Processors

  • Supported Cores: 8 to 60 cores per CPU (e.g. Xeon Gold 6326, 6330N, 8352, 8380)

  • Base Frequency: ~2.1 GHz to ~3.6 GHz depending on model

  • Max TDP: ~105 W to 270 W per processor

  • Supported CPUs: Up to two 3rd Generation Intel Xeon Scalable processors (up to 40 cores per processor)

  • Memory Channels: 8 channels per CPU

  • Max TDP: Up to approx. 270 W per processor
Memory (RAM)

  • Type: DDR4 HPE SmartMemory (RDIMM/LRDIMM and Intel Optane Persistent Memory)

  • DIMM Slots: 32 (16 per processor)

  • Max Capacity: Up to 8.1 TB using RDIMM/LRDIMM, or up to 11.2 TB with Intel Optane Persistent Memory

  • Speed: Up to 3200 MT/s (depending on CPU and memory type)

  • Memory Type: DDR4 RDIMM or LRDIMM ECC

  • DIMM Slots: Up to 32 DIMM slots (16 per CPU)

  • Max Capacity: Up to 2 TB RDIMM or up to 8 TB LRDIMM

  • Speed: Up to 3200 MT/s; supports Intel Optane Persistent Memory 200 Series (up to 8 modules per CPU)
Storage

  • Front Drive Bays: Multiple chassis options:

    • 8SFF standard (expandable to 24SFF)

    • 8LFF standard (expandable to 12LFF)



  • Rear/Mid Tray Options: Optional 6SFF rear, 8SFF mid tray, LFF mid tray

  • Supported Drive Types: SAS, SATA, NVMe (U.2/U.3 with tri-mode controllers)

  • M.2 Boot: Optional M.2 SATA boot or NVMe boot support

  • Drive Bay Options: Supports up to 24 NVMe drives; various configurations of 2.5 SAS/SATA or NVMe (e.g. 8, 16, or 24 SFF)

  • Controllers: Internal: PERC H745, H755, H755N, H345, HBA355i, S150; External: H840; Software RAID options
Expansion / Connectivity

  • PCIe Slots: Up to 9 expansion slots (PCIe Gen4) depending on riser configuration

  • OCP Networking: 1× OCP 3.0 x16 mezzanine slot (flexible networking/storage)

  • PCIe Slots: Up to 8 PCIe Gen 4 expansion slots (full-height/low-profile depending on riser configuration)

  • Networking: Embedded 2 × 1 GbE LOM; optional mezzanine & GPU support
Redundancy & Reliability

  • Power Supplies: Redundant hot-plug Flex Slot Platinum power (e.g., 800W)

  • Cooling: Standard fans; high performance fan option required for NVMe or GPU configs

  • Power Supplies: Dual hot plug redundant PSUs: 700 W mixed mode Titanium, 800 W Platinum, 1100 W Titanium or 1400 W Platinum (AC or DC options)

  • Cooling: Advanced cooling design; supports up to 6 fans and optional liquid cooling
Operating System Support

  • Microsoft Windows Server 2019 / 2022

  • Red Hat Enterprise Linux (RHEL)

  • SUSE Linux Enterprise Server (SLES)

  • VMware ESXi (7.x / 8.x)

  • Other: Ubuntu, Oracle Linux, Citrix XenServer

  • Microsoft Windows Server with Hyper V

  • Red Hat Enterprise Linux

  • SUSE Linux Enterprise Server

  • VMware ESXi / vSAN

  • Canonical Ubuntu Server LTS
Security Features

  • Silicon Root of Trust: Secures firmware and processor identity at ROM-level

  • Secure Boot & Erase: Ensures verified, tamper resistant system startup and clean decommission

  • iLO 5 Security Enhancements: Server Configuration Lock, iLO Security Dashboard, BIOS advisor

  • Cryptographically signed firmware; Silicon Root of Trust

  • Secure Boot, Secure Erase, System Lockdown (requires iDRAC9 Enterprise/Datacenter)

  • TPM 2.0 (FIPS and CC TCG certified)
Management & Monitoring

  • iLO 5: Embedded management for remote control, firmware updates, monitoring

  • Tools: HPE InfoSight (predictive analytics), OneView, Intelligent Provisioning

  • APIs: Redfish, RESTful, SNMP v3, IPMI 2.0

  • iDRAC9 with Lifecycle Controller; RESTful Redfish API; iDRAC Service Module

  • Tools: Dell OpenManage Enterprise, CloudIQ; integrations with VMware, Microsoft System Center, Ansible, Terraform
Warranty & Support

  • Standard Warranty: 3 Years Parts, 3 Years Labor, 3 Years Onsite (Next Business Day)

  • Optional Services: HPE Pointnext Tech Care, Foundation Care, Proactive Care

  • Standard Warranty: 3 Year Dell Basic Hardware Warranty with Next Business Day Onsite Service

  • Optional Extended Support: Dell ProSupport or ProSupport Plus available for extension beyond 3 years

Key Features Comparison

High Performance for Intensive Workloads
Powered by 3rd Gen Intel® Xeon® Scalable Processors, the DL380 Gen10 Plus delivers exceptional performance, making it ideal for data-intensive applications.
Scalable Storage Solutions
Offers flexible storage options, from SATA and SAS HDDs to high-speed NVMe SSDs, providing businesses with the storage configurations they need.
Advanced Security Features
Built with HPE Silicon Root of Trust, a robust security framework that ensures secure boot and protects against unauthorized firmware modifications.
Flexible Expansion and Connectivity
The DL380 Gen10 Plus supports PCIe Gen4, enabling high-speed expansion for enhanced networking and storage capabilities.
Energy Efficient
Designed for lower power consumption without sacrificing performance, reducing operational costs and supporting eco-friendly initiatives.
Redundant Power Supplies and Cooling
Ensures reliability with dual power supplies and optimized cooling, minimizing downtime and maximizing productivity.
High Performance and Scalability
Powered by the latest Intel Xeon Scalable processors, the Dell PowerEdge R750 delivers exceptional performance and can scale to meet the demands of growing businesses.
Advanced Security Features
Built-in security measures of the Dell PowerEdge R750 protect your data with end-to-end encryption and secure boot capabilities, ensuring your information remains safe.
Efficient Management
Dell’s OpenManage systems management solutions provide simplified and efficient management of your Dell PowerEdge R750 server infrastructure, reducing complexity and operational costs.
Versatile Configuration Options
The Dell PowerEdge R750 supports a wide range of configurations with up to 24 NVMe drives, enabling customization to meet specific business requirements
Enhanced Storage Capacity
The Dell PowerEdge R750 offers extensive storage options with support for both SAS and SATA drives, providing flexibility and scalability for data storage needs
Energy Efficiency
Designed with energy-efficient technologies, the Dell PowerEdge R750 helps reduce power consumption and operational costs, making it an eco-friendly choice for your data center

HPE ProLiant DL380 Gen10 Plus Server vs Dell PowerEdge R750 Rack Server : Which should I choose?

Choosing the right server is a critical decision for any business, and comparing HPE ProLiant DL380 Gen10 Plus Server and Dell PowerEdge R750 Rack Server gives you clear insights into which solution aligns best with your IT requirements. These servers are built for high performance, but they may differ in areas such as processor capacity, memory, storage, and scalability, making a side-by-side comparison easy.

This direct comparison helps you quickly identify the strengths and limitations of each server, which helps you determine which model best supports your workloads, applications, and long-term IT goals. By evaluating them together, you can make a smarter investment that ensures reliability and efficiency for your business.

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