Quick Comparison of HPE ProLiant Compute DL380 Gen12 vs PowerEdge R770 Rack Server at a Glance

The server comparison table provides a quick overview of the key specifications and key features for HPE ProLiant Compute DL380 Gen12 and PowerEdge R770 Rack Server Let’s take a look at the comparison table below.

Features	HPE ProLiant Compute DL380 Gen12 View Check the Price	PowerEdge R770 Rack Server View Check the Price
Server Type / Form Factor	Type:Enterprise Rack Server Form Factor: 2U Rack Socket: Dual?socket (supports 1 or 2 Intel Xeon 6 processors)	Type: Enterprise Rack Server Form Factor: 2U Rack Socket: Dual-socket (2 x Intel Xeon 6 Processors)
Processor (CPU)	Processor Family: Intel Xeon 6 Scalable Processors Max Sockets: 2 Cores per Socket: Up to 144 cores Max Speed: Up to 3.9 GHz (varies by processor model) Memory Channels: 8 channels per processor	Processor Family: Intel Xeon 6 (E-core and P-core series) Max Sockets: 2 Max Cores per Socket: Up to 144 E-cores or 86 P-cores Max TDP: Up to 500 W per processor Max L3 Cache: Up to 480 MB per processor (varies by SKU)
Memory (RAM)	Memory Type: HPE DDR5 Smart Memory (RDIMM) DIMM Slots: 32 DIMM slots (16 per processor, 2 DIMMs per channel) Maximum Capacity: Up to 8 TB (with 256 GB modules) Maximum Speed: Up to 6400 MT/s at 1DPC (depends on CPU and DIMM population) Memory Protection: Advanced ECC, online spare, mirroring, combined channel (lockstep)	Memory Type: DDR5 RDIMM (registered ECC only) DIMM Slots: 32 DIMM slots (16 per processor) Maximum Capacity: Up to 8 TB Speed: Up to 6400 MT/s Protection: ECC with advanced RAS features
Storage	Front Drive Options: Up to 36 EDSFF E3.S NVMe drives Additional Drive Options: Up to 24 SFF bays (SAS/SATA/NVMe) LFF Bays: Up to 12 LFF bays (SAS/SATA) Max Internal Storage: 550.8 TB using 36 x 15.3 TB EDSFF NVMe Alternative Capacity: 480 TB using LFF SAS/SATA SSDs in 12+4+4 configuration RAID Support: HPE Smart Array controllers (RAID 0, 1, 5, 6, 10, 50, 60 – depending on controller)	Drive Bay Options: Up to 16 x EDSFF E3.S NVMe Configuration Option: 24 x 2.5-inch SAS/SATA/NVMe Configuration Option: 12 x 3.5-inch SAS/SATA Hybrid Configurations: Supported Supported Drives: SAS, SATA, NVMe SSD/HDD (2.5-inch, 3.5-inch, EDSFF E3.S) RAID Support: PERC H365i/H965i/H975i controllers (RAID 0, 1, 5, 6, 10, 50, 60)
Expansion / Connectivity	PCIe Slots: Multiple PCIe 5.0 slots (including up to four PCIe x16 full-height, full-length slots) OCP Slots: Up to two front OCP 3.0 slots for high-speed NICs or accelerators Networking: OCP 3.0 FlexibleLOM (choices of 1/10/25/100GbE) GPU Support: GPU-accelerated configurations and GPU-performance kits available for AI and HPC workloads	PCIe Slots: Up to 8 PCIe Gen5 slots (mix of x8/x16 full-height/full-length) OCP Slots: Up to 2 OCP NIC 3.0 (1/10/25/100/400 GbE) Networking: 1 GbE BMC + PCIe add-in cards (InfiniBand, 400 GbE, FC) GPU / Accelerator Support: Multiple GPU options with optional Direct Liquid Cooling
Redundancy & Reliability	Power: Redundant hot-plug power supplies (various wattages and efficiency grades) Cooling: Redundant hot-plug fans; optional direct-liquid cooling-compatible designs Storage: Hot-swap drive bays and RAID-based redundancy options Availability Features: HPE-engineered reliability, service-level-ready architectures	Power: Redundant hot-plug PSUs (800W–3200W Platinum/Titanium) Cooling: Redundant hot-swap fans; optional Direct Liquid Cooling (DLC) Reliability: Hot-swap components, OCP DC-MHS modular design
Operating System Support	Microsoft Windows Server Red Hat Enterprise Linux (RHEL) SUSE Linux Enterprise Server (SLES) VMware ESXi Canonical Ubuntu Oracle Linux	Microsoft Windows Server with Hyper-V Red Hat Enterprise Linux (RHEL) Canonical Ubuntu Server LTS VMware ESXi SUSE Linux Enterprise Server (SLES)
Security Features	Silicon Root of Trust Secure Boot, Secure Start Intel TME (Total Memory Encryption) Firmware and Runtime Integrity Monitoring UEFI-managed encryption and privilege-separation controls Industry-standard compliance (ACPI 6.5, PCIe 5.0, PXE, Wake-on-LAN)	Dell SafeBIOS Secure Core System Lockdown and Cryptographic Erase Firmware Update Verification and TPM 2.0 Secure Boot and Multi-Factor Authentication
Management & Monitoring	HPE iLO 7: Embedded management for remote console, BIOS setting, firmware updates, and alerts HPE Compute Ops Management: AI-driven operations dashboard and lifecycle automation APIs: RESTful / Redfish-based interfaces for integration with third-party tools	iDRAC10 Enterprise: Embedded remote management Dell OpenManage Enterprise: AI-driven centralized management APIs: Redfish APIs and RESTful interfaces for automation
Warranty & Support	Standard Warranty: 3 Years Parts, 3 Years Labor, 3 Years Onsite (varies by region and contract) Optional Support: HPE Pointnext, Foundation Care, Proactive Care, and custom SLAs	Standard Warranty: 3 Years ProSupport (parts, labor, onsite) Optional Support: ProSupport Plus, ProSupport Enterprise, extended terms, AI-driven proactive analytics

Key Features Comparison

High Performance Compute

The HPE ProLiant Compute DL380 Gen12 is a 2U rack server built on Intel Xeon 6 processors, supporting up to two processors with up to 144 cores per socket, enabling higher instructions per clock and up to significantly higher performance versus prior generations for demanding compute workloads

Large, High Speed Memory Capacity

It supports up to 8 TB of HPE DDR5 Smart Memory across 32 DIMM slots (16 per processor), with speeds up to 6400 MT/s at 1 DIMM per channel, delivering substantial headroom for virtualization, databases, and analytics

Flexible High-Speed Storage Options

The server offers multiple front-drive configurations including up to 36 EDSFF E3.S NVMe drives, 24 SFF bays, or 12 LFF bays, with maximum internal storage capacities reaching 550.8 TB using 36 x 15.3 TB EDSFF NVMe drives.

Advanced PCIe 5.0 Expansion & GPU Support

Powered by PCIe Gen5, the DL380 Gen12 provides up to four PCIe x16 full-height slots plus riser-based expansion, improving I/O throughput and latency; the platform also supports front OCP NICs and GPU-accelerated options, including GPU-performance kits for optimized thermal and power delivery.

Next-Generation Security & Firmware Protection

The server includes Intel Xeon 6 security features such as Intel TME (Total Memory Encryption) and HPE-specific protections such as Silicon Root of Trust, secure boot, and firmware integrity monitoring, helping safeguard data at boot, in-use, and at rest.

AI-Driven Management with HPE iLO 7

Equipped with HPE iLO 7, the DL380 Gen12 delivers embedded remote management, BIOS-level tuning, firmware updates, and Redfish-based APIs, while HPE Compute Ops Management provides AI-driven insights and lifecycle automation to simplify operations and reduce downtime.

High-Performance Dual-Socket Intel Compute

The Dell PowerEdge R770 is a 2U rack server supporting dual Intel Xeon 6 Processors with up to 144 E-cores or 86 P-cores per processor (288 E-cores or 172 P-cores total), delivering exceptional performance for virtualization, AI, analytics, and mission-critical workloads.

Ultra-High DDR5 Memory Capacity

Supports up to 8 TB of DDR5 memory across 32 DIMM slots with speeds up to 6400 MT/s, providing massive headroom for memory-intensive applications like databases, in-memory analytics, and AI model training.

Flexible High-Density Storage

Offers multiple drive configurations including up to 16 x EDSFF E3.S NVMe drives, 24 x 2.5-inch SAS/SATA/NVMe, or 12 x 3.5-inch options, enabling scalable storage for cloud, edge, and data-intensive environments.

PCIe Gen5 Expansion & AI-Ready Design

Built on PCIe Gen5, it provides up to 8 PCIe slots (including x16 full-height) plus 2 OCP NIC 3.0 cards, supporting GPUs, accelerators, and 400 GbE networking with optional Direct Liquid Cooling (DLC) for AI and HPC workloads.

Advanced Security & iDRAC10 Management

Features Dell SafeBIOS Secure Core, system lockdown, cryptographic erase, and firmware integrity verification, paired with iDRAC10 Enterprise for AI-driven management, OpenManage Enterprise, and Redfish APIs for automation.

Modular & Power-Efficient Architecture

Uses OCP DC-MHS modular design with redundant hot-swap PSUs (up to 3200W Titanium) and tool-less serviceability, optimizing power efficiency and scalability for dense racks and sustainable data centers.

HPE ProLiant Compute DL380 Gen12 vs PowerEdge R770 Rack Server : Which should I choose?

Choosing the right server is a critical decision for any business, and comparing HPE ProLiant Compute DL380 Gen12 and PowerEdge R770 Rack Server gives you clear insights into which solution aligns best with your IT requirements. These servers are built for high performance, but they may differ in areas such as processor capacity, memory, storage, and scalability, making a side-by-side comparison easy.

This direct comparison helps you quickly identify the strengths and limitations of each server, which helps you determine which model best supports your workloads, applications, and long-term IT goals. By evaluating them together, you can make a smarter investment that ensures reliability and efficiency for your business.

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