Quick Comparison of HPE ProLiant ML110 Gen10 Server vs Lenovo ThinkSystem ST50 Server at a Glance

The server comparison table provides a quick overview of the key specifications and key features for HPE ProLiant ML110 Gen10 Server and Lenovo ThinkSystem ST50 Server Let’s take a look at the comparison table below.

Features	HPE ProLiant ML110 Gen10 Server View Check the Price	Lenovo ThinkSystem ST50 Server View Check the Price
Server Type / Form Factor	Type: Tower Server (upgradeable to rack mount with optional kit) Form Factor: 4.5U Tower Socket: Single socket (supports 1 Intel Xeon Scalable CPU)	Type: Tower Server Form Factor: Small-form-factor Tower; optional rack-mount kit Socket: Single socket (Intel Xeon E 2100 or E 2200 series up to 6 cores; also supports Intel Pentium, Core i3, Celeron up to 4 cores)
Processor (CPU)	Processor Family: Intel Xeon Scalable (1st and 2nd Generation) Core Options: 4, 6, 8 or up to 14 cores (e.g. Xeon Silver 4210, 4210R, Gold 5222) Max Frequency: Up to ~3.6 GHz Max TDP: Up to ~110 W Memory Capacity (per socket): Up to 192 GB with 6 × 32 GB RDIMM	Supported CPUs: One Intel Xeon E 2100 or E 2200 series (up to 6 cores) Also supports: Intel Core i3, Pentium G5xx0/D/T, or Celeron G4900-series (up to 4 cores)
Memory (RAM)	Type: DDR4 HPE SmartMemory (RDIMM only) DIMM Slots: 6 slots (1 DIMM per channel across 6 memory channels) Max Capacity: 192 GB (6 × 32 GB at 2933 MT/s for Gen2 CPUs) Speed: Up to 2933 MT/s (depending on CPU model)	Memory Type: TruDDR4 ECC UDIMM DIMM Slots: 4 slots total Max Capacity: Up to 64 GB (4×16 GB at 2666 MT/s) Speed: 2666 MT/s for supported modules
Storage	Drive Bays: Up to 8 × LFF (hot plug SATA/SAS) or 16 × SFF (hot plug) Controller: HPE Smart Array S100i SR Gen10 (software RAID), or optional P408i p, E208i p HW controllers Boot Options: Optional M.2 module or SATA/eMMC boot (UEFI only)	Drive Bay Options: Up to 4 × 3.5 non hot swap SATA/SAS HDD or SSD Bay 4 convertible to optical/tape or 3.5 drive via conversion kit Supports 2 × SD cards or dual SD RAID Controllers: Intel VROC software RAID or optional hardware RAID adapters
Expansion / Connectivity	PCIe Slots: 5 × PCIe 3.0 slots (mix of x16 and x8 slots) Networking: Embedded dual-port 1 GbE (Intel 332i); optional FlexibleLOM mezzanine for higher-throughput NICs	PCIe Slots: Up to 3 slots: one x16 Gen 3, one x1 Gen 3, one x16 Gen 3 (or x4 lanes) Networking: Embedded 1 GbE (Broadcom or Intel) plus optional NIC via PCIe
Redundancy & Reliability	Power Supply: 350 W or 550 W ATX PSUs; optional 800 W Flex Slot hot plug PSU Cooling: Standard 2 non hot plug fans; optional redundant fan kit recommended for high RPM drives or SAS SSDs Security: Silicon Root of Trust, UEFI Secure Boot, Secure Recovery, Runtime Firmware Validation	Power Supplies: Single fixed PSU only—250 W Platinum or 400 W Bronze efficiency (non redundant) Cooling: Quiet office environment cooling with front and rear case fans
Operating System Support	Microsoft Windows Server 2016 / 2019 / 2022 Red Hat Enterprise Linux (RHEL) SUSE Linux Enterprise Server (SLES) VMware ESXi (vSphere 6.7 U3, 7.x, 8.x) ClearOS, CentOS, Ubuntu, Oracle Linux	Microsoft Windows Server Red Hat Enterprise Linux SUSE Linux Enterprise Server VMware ESXi CentOS
Security Features	iLO 5 Security: Configurable server lock, BIOS Advisor, security dashboard TPM 2.0 Support: Optional FIO module Firmware Security: Secure Boot, Firmware rollback, Runtime Validation	Lenovo XClarity Provisioning Manager or Intel AMT (entry level) Embedded TPM 2.0 Optional chassis intrusion switch
Management & Monitoring	Embedded: HPE iLO Standard with Intelligent Provisioning Optional Licenses: iLO Advanced, iLO Advanced Premium Security Edition Tools: Active Health System, iLO RESTful API, OneView Standard, iLO Amplifier Pack	Intel AMT and Lenovo USB based XClarity Provisioning Manager Optional remote management via XClarity Administrator suite
Warranty & Support	Standard: 3 Year Parts, 3 Year Labor, 3 Year Onsite (Next Business Day) Service Options: HPE Pointnext Tech Care, Foundation Care, Proactive Care	Standard Warranty: 3 Years Warranty Support Options: Warranty extensions available via Lenovo support offerings

Key Features Comparison

Cost-Effective Performance

Powered by Intel® Xeon® Scalable processors, the ML110 Gen10 provides enterprise-grade performance at a budget-friendly price, making it an excellent choice for small to medium businesses.

Compact Tower Design

Its compact, quiet tower design is ideal for small offices and remote branch environments, saving valuable space without compromising performance.

Flexible Storage Options

Supports up to 8 LFF (Large Form Factor) or 16 SFF (Small Form Factor) drive bays, enabling businesses to choose storage configurations that suit their workloads, from HDDs to SSDs.

Enhanced Security Features

Equipped with HPE’s Silicon Root of Trust, protecting your server against firmware-level threats and ensuring data integrity across operations.

Energy Efficient and Quiet Operation

Designed to reduce power consumption and operate quietly, making it ideal for in-office deployments where energy efficiency and low noise are essential.

Simplified Management with HPE iLO 5

HPE’s Integrated Lights-Out (iLO) 5 provides easy remote management, streamlining server maintenance, monitoring, and security for IT administrators.

Entry-Level Performance

The Lenovo ThinkSystem ST50 is powered by Intel Xeon E-2100 series processors, which deliver reliable performance for small and medium-sized businesses

Compact Design

Its compact tower form factor saves space and makes it easy to use in office areas.

Scalability

Supports up to 64GB of DDR4 memory and a variety of storage options including SATA HDDs and SSDs, ensuring flexibility for future upgrades

Energy Efficient

Designed for low energy consumption, the ST50 helps reduce operating costs while maintaining efficiency.

Remote Management

Built-in Lenovo XClarity Controller for easy remote server management and monitoring

Quiet Operation

Runs quietly, making it ideal for office environments where noise must be reduced

HPE ProLiant ML110 Gen10 Server vs Lenovo ThinkSystem ST50 Server : Which should I choose?

Choosing the right server is a critical decision for any business, and comparing HPE ProLiant ML110 Gen10 Server and Lenovo ThinkSystem ST50 Server gives you clear insights into which solution aligns best with your IT requirements. These servers are built for high performance, but they may differ in areas such as processor capacity, memory, storage, and scalability, making a side-by-side comparison easy.

This direct comparison helps you quickly identify the strengths and limitations of each server, which helps you determine which model best supports your workloads, applications, and long-term IT goals. By evaluating them together, you can make a smarter investment that ensures reliability and efficiency for your business.

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