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Quick Comparison of HPE ProLiant DL385 Gen11 Server vs HPE ProLiant DL380 Gen11 Server at a Glance

The server comparison table provides a quick overview of the key specifications and key features for HPE ProLiant DL385 Gen11 Server and HPE ProLiant DL380 Gen11 Server Let’s take a look at the comparison table below.

Features
HPE ProLiant DL385 Gen11 Server

HPE ProLiant DL385 Gen11 Server

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HPE ProLiant DL380 Gen11 Server

HPE ProLiant DL380 Gen11 Server

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Server Type / Form Factor

  • Type: Rack Server

  • Form Factor: 2U Rackmount

  • Socket: Dual-socket (supports up to 2 processors)

  • Type: Rack Server

  • Form Factor: 2U Rackmount

  • Socket: Dual-socket (supports up to 2 processors)
Processor (CPU)

  • Processor Family: AMD EPYC™ 9004 Series

  • Max Supported: Up to AMD EPYC 9654 (96 cores, 192 threads)

  • Architecture: 5nm, Zen 4

  • Max TDP: Up to 400W per processor

  • Processor Family: 4th and 5th Gen Intel® Xeon® Scalable Processors

  • Max Supported: Up to 60 cores per processor (e.g., Intel Xeon Gold 6490N)

  • Architecture: Intel 7 (10nm Enhanced SuperFin)

  • Max TDP: Up to 350W per processor
Memory (RAM)

  • Type: DDR5 Registered DIMMs (RDIMMs)

  • DIMM Slots: 24 (12 per CPU)

  • Max Capacity: Up to 6TB

  • Speed: Up to 5600 MT/s

  • Protection: ECC, Mirroring, Fast Failover

  • Type: DDR5 Registered DIMMs (RDIMMs)

  • DIMM Slots: 32 DIMM slots (16 per CPU)

  • Max Capacity: Up to 8TB (with Intel Optane Persistent Memory)

  • Speed: Up to 5600 MT/s (depends on CPU and DIMM configuration)

  • Protection: ECC, Mirroring, Lockstep, Fast Fault Tolerance
Storage

  • Drive Bays: Up to 12x LFF or 24x SFF (front)

  • Rear Drives: Optional 2x SFF or NVMe

  • Supported Types: SAS, SATA, NVMe

  • RAID: HPE Smart Array (RAID 0, 1, 5, 6, 10, 50, 60)

  • Max Capacity: Over 400TB (based on configuration)

  • Drive Bays: Up to 12x LFF or 24x SFF (front)

  • Rear Drives: Optional up to 6x SFF/NVMe

  • Supported Types: SAS, SATA, NVMe

  • RAID: HPE Smart Array Controllers (RAID 0, 1, 5, 6, 10, 50, 60)

  • Max Capacity: Over 400TB+ depending on configuration
Expansion / Connectivity

  • PCIe Slots: Up to 8x PCIe Gen5

  • Networking: OCP 3.0 Slot (1/10/25/100GbE options)

  • GPU Support: Up to 4x Single-width or 3x Double-width GPUs

  • PCIe Slots: Up to 8x PCIe Gen5 (varies by riser config)

  • Networking: OCP 3.0 FlexibleLOM (1/10/25/100GbE options)

  • GPU Support: Supports multiple GPUs (up to 3 double-wide or 6 single-wide)
Redundancy & Reliability

  • Power: Redundant Hot-Plug Power Supplies (800W–2400W)

  • Cooling: Redundant Hot-Plug Fans

  • Drive Redundancy: RAID support

  • Firmware Security: HPE Silicon Root of Trust

  • Power: Redundant Hot-Plug Power Supplies (800W, 1600W, 2400W)

  • Cooling: Redundant Hot-Plug Fans

  • Drive Redundancy: RAID options for redundancy

  • Security: HPE Silicon Root of Trust
Operating System Support

  • Microsoft Windows Server

  • Red Hat Enterprise Linux (RHEL)

  • SUSE Linux Enterprise Server (SLES)

  • VMware ESXi

  • Ubuntu, Oracle Linux, ClearOS

  • Microsoft Windows Server

  • Red Hat Enterprise Linux (RHEL)

  • SUSE Linux Enterprise Server (SLES)

  • VMware ESXi

  • Canonical Ubuntu

  • Oracle Linux
Security Features

  • Silicon Root of Trust

  • Secure Boot & Secure Erase

  • TPM 2.0 (FIPS-certified optional)

  • Firmware Verification & Intrusion Detection

  • HPE Silicon Root of Trust

  • Secure Boot & Secure Erase

  • TPM 2.0 (Standard, with optional FIPS certification)

  • Chassis Intrusion Detection

  • Firmware & Runtime Verification
Management & Monitoring

  • iLO 6: Integrated Lights-Out Management

  • Tools: HPE OneView, InfoSight, Redfish API

  • Remote Access: Firmware Updates, Monitoring, Alerting

  • iLO 6: HPE Integrated Lights-Out 6 for remote server management

  • Tools: HPE OneView, InfoSight Predictive Analytics

  • APIs: RESTful API, Redfish Support
Warranty & Support

  • Warranty: 3-Year Parts, 3-Year Labor, 3-Year Onsite (Next Business Day)

  • Optional Support: HPE Pointnext, Foundation Care, Proactive Care

  • Standard Warranty: 3 Years Parts, 3 Years Labor, 3 Years Onsite (Next Business Day)

  • Optional Support: HPE Pointnext, Foundation Care, and Proactive Care Services

Key Features Comparison

Enhanced Performance
Powered by the latest AMD EPYC™ 9004 Series processors, the HPE ProLiant DL385 Gen11 delivers superior performance and high-speed processing to handle even the most data-intensive applications.
Scalable Storage and Memory
Offers flexible storage options, supporting up to 184TB, and up to 8TB of DDR5 memory, enabling efficient handling of high-performance workloads, virtualization, and large databases.
Advanced Security Features
The server supports a variety of storage systems, including NVMe SSDs and SAS/SATA HDDs, so you can tailor your storage solution to meet your specific needs From fast data traffic up to ample storage the DL385 Gen11 offers the flexibility you need.
Virtualization and Cloud-Ready
Ideal for virtualized environments, this server supports software-defined infrastructures and is optimized for cloud deployments, making it a great choice for enterprises looking to streamline their digital transformation.
Energy Efficiency
Engineered for energy efficiency, the DL385 Gen11 minimizes power usage, helping businesses reduce operating costs while aligning with environmental goals.
High I/O Capacity
With support for PCIe Gen5, the server delivers higher data throughput and faster connectivity options, allowing faster processing and data transfer rates.
High Performance
Powered by the latest Intel® Xeon® Scalable processors, offering up to 60% increased performance and 27% more cores for demanding workloads.
Enhanced Security
Comes with HPE iLO 5 security features, including Server Configuration Lock and the iLO Security Dashboard for robust data protection.
Flexible Storage Options
Supports up to 30 SFF or 20 NVMe drive bays, allowing for scalable storage solutions to match business growth.
Advanced GPU Support
Accommodates up to 3 double-wide GPUs, making it ideal for AI, machine learning, and deep learning workloads.
Energy-Efficient Operation
ENERGY STAR® certified, ensuring reduced power consumption and operational costs while maintaining top performance.
Comprehensive Manageability
Features HPE InfoSight for predictive analytics and proactive support, enhancing uptime and reliability through AI-driven management.

HPE ProLiant DL385 Gen11 Server vs HPE ProLiant DL380 Gen11 Server : Which should I choose?

Choosing the right server is a critical decision for any business, and comparing HPE ProLiant DL385 Gen11 Server and HPE ProLiant DL380 Gen11 Server gives you clear insights into which solution aligns best with your IT requirements. These servers are built for high performance, but they may differ in areas such as processor capacity, memory, storage, and scalability, making a side-by-side comparison easy.

This direct comparison helps you quickly identify the strengths and limitations of each server, which helps you determine which model best supports your workloads, applications, and long-term IT goals. By evaluating them together, you can make a smarter investment that ensures reliability and efficiency for your business.

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