Quick Comparison of HPE ProLiant DL380 Gen11 Server vs Lenovo ThinkSystem SR650 V4 at a Glance

The server comparison table provides a quick overview of the key specifications and key features for HPE ProLiant DL380 Gen11 Server and Lenovo ThinkSystem SR650 V4 Let’s take a look at the comparison table below.

Features	HPE ProLiant DL380 Gen11 Server View Check the Price	Lenovo ThinkSystem SR650 V4 View Check the Price
Server Type / Form Factor	Type: Rack Server Form Factor: 2U Rackmount Socket: Dual-socket (supports up to 2 processors)	Type: Enterprise Rack Server Form Factor: 2U Rack Socket: Dual-socket (2x Intel Xeon 6 processors)
Processor (CPU)	Processor Family: 4th and 5th Gen Intel® Xeon® Scalable Processors Max Supported: Up to 60 cores per processor (e.g., Intel Xeon Gold 6490N) Architecture: Intel 7 (10nm Enhanced SuperFin) Max TDP: Up to 350W per processor	Processor Family: Intel Xeon 6 (6700/6500-series P-cores, Granite Rapids-SP) Max Sockets: 2 Max Cores per Socket: Up to 86 cores Max TDP: Up to 350 W per processor Socket Type: LGA 4710
Memory (RAM)	Type: DDR5 Registered DIMMs (RDIMMs) DIMM Slots: 32 DIMM slots (16 per CPU) Max Capacity: Up to 8TB (with Intel Optane Persistent Memory) Speed: Up to 5600 MT/s (depends on CPU and DIMM configuration) Protection: ECC, Mirroring, Lockstep, Fast Fault Tolerance	Memory Type: TruDDR5 (RDIMM, 3DS RDIMM, MRDIMM) DIMM Slots: 32x TruDDR5 RDIMMs + 16x MRDIMMs Maximum Capacity: Up to 8 TB Speed: Up to 6400 MHz (RDIMM), 8000 MHz (MRDIMM) Protection: Advanced ECC, RAS features
Storage	Drive Bays: Up to 12x LFF or 24x SFF (front) Rear Drives: Optional up to 6x SFF/NVMe Supported Types: SAS, SATA, NVMe RAID: HPE Smart Array Controllers (RAID 0, 1, 5, 6, 10, 50, 60) Max Capacity: Over 400TB+ depending on configuration	Front Drive Bays: 24x 2.5" SAS/SATA/NVMe, 32x E3.S NVMe, or 12x 3.5" bays Mid Drive Bays: Up to 8x 2.5" SAS/SATA/NVMe Rear Drive Bays: Up to 8x 2.5" or 4x 3.5" SAS/SATA/NVMe Boot Drives: Up to 2x M.2 SATA/NVMe with RAID RAID Support: VROC NVMe SW RAID (0,1,5,10), PCIe RAID/HBA
Expansion / Connectivity	PCIe Slots: Up to 8x PCIe Gen5 (varies by riser config) Networking: OCP 3.0 FlexibleLOM (1/10/25/100GbE options) GPU Support: Supports multiple GPUs (up to 3 double-wide or 6 single-wide)	PCIe Slots: Up to 10x PCIe Gen5 slots OCP Slots: 2x OCP 3.0 slots Networking: OCP adapters, PCIe 10/25/100/200 GbE GPU Support: Up to 10x SW GPUs or 2x DW GPUs
Redundancy & Reliability	Power: Redundant Hot-Plug Power Supplies (800W, 1600W, 2400W) Cooling: Redundant Hot-Plug Fans Drive Redundancy: RAID options for redundancy Security: HPE Silicon Root of Trust	Power: Dual redundant AC/DC PSUs (Platinum/Titanium efficiency) Cooling: Lenovo Neptune Core/Air technology, redundant fans Reliability: Six nines uptime, hot-swap components
Operating System Support	Microsoft Windows Server Red Hat Enterprise Linux (RHEL) SUSE Linux Enterprise Server (SLES) VMware ESXi Canonical Ubuntu Oracle Linux	Microsoft Windows Server Red Hat Enterprise Linux (RHEL) SUSE Linux Enterprise Server (SLES) VMware ESXi
Security Features	HPE Silicon Root of Trust Secure Boot & Secure Erase TPM 2.0 (Standard, with optional FIPS certification) Chassis Intrusion Detection Firmware & Runtime Verification	Lenovo ThinkShield security suite Silicon Root of Trust Secure Boot and fTPM 2.0 Federated directory security
Management & Monitoring	iLO 6: HPE Integrated Lights-Out 6 for remote server management Tools: HPE OneView, InfoSight Predictive Analytics APIs: RESTful API, Redfish Support	Lenovo XClarity Controller: Embedded management XClarity One: AI-driven analytics APIs: Redfish APIs for automation
Warranty & Support	Standard Warranty: 3 Years Parts, 3 Years Labor, 3 Years Onsite (Next Business Day) Optional Support: HPE Pointnext, Foundation Care, and Proactive Care Services	Standard Warranty: 3 Years Customer Replaceable Unit, Onsite NBD 9x5 Optional Support: Premier Support, TruScale Infrastructure Services

Key Features Comparison

High Performance

Powered by the latest Intel® Xeon® Scalable processors, offering up to 60% increased performance and 27% more cores for demanding workloads.

Enhanced Security

Comes with HPE iLO 5 security features, including Server Configuration Lock and the iLO Security Dashboard for robust data protection.

Flexible Storage Options

Supports up to 30 SFF or 20 NVMe drive bays, allowing for scalable storage solutions to match business growth.

Advanced GPU Support

Accommodates up to 3 double-wide GPUs, making it ideal for AI, machine learning, and deep learning workloads.

Energy-Efficient Operation

ENERGY STAR® certified, ensuring reduced power consumption and operational costs while maintaining top performance.

Comprehensive Manageability

Features HPE InfoSight for predictive analytics and proactive support, enhancing uptime and reliability through AI-driven management.

Versatile Dual-Socket Intel Compute

The Lenovo ThinkSystem SR650 V4 is a 2U rack server powered by dual Intel Xeon 6 processors (up to 86 cores per socket, 350W TDP), optimized for virtualization, databases, hybrid cloud, analytics, and AI workloads with industry-leading reliability.

Ultra-High TruDDR5 Memory Capacity

Supports up to 8TB TruDDR5 memory across 32 DIMM slots (RDIMMs/3DS RDIMMs up to 6400MHz) plus 16x MRDIMMs up to 8000MHz, delivering massive scalability for memory-intensive enterprise applications.

Flexible High-Density Storage

Offers front: up to 24x 2.5" SAS/SATA/NVMe, 32x E3.S NVMe, or 12x 3.5", mid: 8x 2.5", rear: 8x 2.5" or 4x 3.5", plus 2x M.2 boot drives with RAID, supporting Direct NVMe and VROC/VMD for modern storage needs.

PCIe Gen5 & GPU Expansion

Provides up to 10x PCIe Gen5 slots plus 2x OCP 3.0, supporting up to 10x single-width GPUs or 2x double-width GPUs for AI training, inference, HPC, and graphics-intensive workloads.

Advanced Security & XClarity Management

Features Lenovo ThinkShield with silicon root of trust, secure boot, fTPM 2.0; XClarity Controller enables AI-driven predictive analytics, remote access, SSD failure analysis, and federated security.

Sustainable Cooling & Efficiency

Lenovo Neptune Core/Air cooling options deliver ENERGY STAR compliance, up to 3:1 rack consolidation, six nines uptime reliability, and reduced TCO for environmentally conscious deployments.

HPE ProLiant DL380 Gen11 Server vs Lenovo ThinkSystem SR650 V4 : Which should I choose?

Choosing the right server is a critical decision for any business, and comparing HPE ProLiant DL380 Gen11 Server and Lenovo ThinkSystem SR650 V4 gives you clear insights into which solution aligns best with your IT requirements. These servers are built for high performance, but they may differ in areas such as processor capacity, memory, storage, and scalability, making a side-by-side comparison easy.

This direct comparison helps you quickly identify the strengths and limitations of each server, which helps you determine which model best supports your workloads, applications, and long-term IT goals. By evaluating them together, you can make a smarter investment that ensures reliability and efficiency for your business.

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