Quick Comparison of HPE ProLiant DL380 Gen10 Server vs Lenovo ThinkSystem SR650 V2 Server at a Glance

The server comparison table provides a quick overview of the key specifications and key features for HPE ProLiant DL380 Gen10 Server and Lenovo ThinkSystem SR650 V2 Server Let’s take a look at the comparison table below.

Features	HPE ProLiant DL380 Gen10 Server View Check the Price	Lenovo ThinkSystem SR650 V2 Server View Check the Price
Server Type / Form Factor	Type: Rack Server Form Factor: 2U Rackmount Socket: Dual socket (supports up to 2 processors)	Type: Rack Server Form Factor: 2U Rackmount Socket: Dual socket (supports up to two 3rd Gen Intel Xeon Scalable processors, up to 40 cores/socket)
Processor (CPU)	Processor Family: Intel Xeon Scalable Processors (1st and 2nd Gen) Supported Cores: 4 to 28 cores per CPU (e.g. Bronze 3200, Silver 4200, Gold 5200/6200 series) Base Frequency: ~1.9 GHz to ~3.2 GHz depending on model Max TDP: ~85 W to ~205 W per processor Memory per Socket: Up to 1 TB (Silver/Gold) or up to 4.5 TB per socket (Large memory tiers with Optane)	Supported CPUs: Up to two 3rd Generation Intel Xeon Scalable processors (up to 40 cores per socket, 270 W TDP)
Memory (RAM)	Type: DDR4 HPE SmartMemory (RDIMM, LRDIMM, DC Persistent Memory) DIMM Slots: 24 slots (12 per processor, 6 channels each) Max Capacity: Up to 2.0 TB using RDIMM @ 2933 MT/s Up to 3.0 TB using LRDIMM @ 2933 or 3200 MT/s Up to 4.5 TB per socket using Intel Optane Persistent Memory (select SKUs)	Memory Type: TruDDR4 RDIMM / 3DS RDIMM ECC DIMM Slots: Up to 32 slots total (16 per CPU) Max Capacity: Up to 8 TB system memory (using 256 GB 3DS RDIMMs); up to 12 TB with persistent memory Speed: Up to 3200 MT/s
Storage	Front Drive Bays: Flexible chassis options: Up to 12 × LFF (3.5") SAS/SATA HDD/SSD Or up to 24 × SFF (2.5") SAS/SATA/NVMe Optional Rear/Mid-Tray: Additional 2–6 SFF or LFF drives Supported Drive Types: SAS, SATA, NVMe U.2/U.3 via tri mode Smart Array controllers Boot Options: Optional M.2 SATA boot module	Drive Bay Options: Front: up to 24 × 2.5 or 12 × 3.5 hot swap drives Middle: up to 8 × 2.5 or 4 × 3.5 hot swap bays Rear: up to 8 × 2.5 or 4 × 3.5 hot swap bays, plus two 7 mm boot drives Boot Options: 2 × internal M.2 SATA/NVMe drives in RAID Controllers: Onboard Intel VROC for SATA/NVMe; optional hardware RAID/HBA adapters
Expansion / Connectivity	PCIe Slots: Up to 8–9 × PCIe 3.0 slots depending on riser configuration Networking: OCP 3.0 mezzanine slot available (for 10/25/100 GbE modules)	PCIe Slots: Up to eight PCIe Gen 4 slots (all rear accessible) plus one OCP 3.0 mezzanine slot; GPU Support: Supports up to eight single width GPUs or three double width GPUs Networking: Embedded LOM + optional OCP adapter for 1/10/25 GbE
Redundancy & Reliability	Power Supplies: Redundant Flex Slot power supplies (e.g., 800 W, 1600 W Platinum) Cooling: Hot-plug fans; high-performance kit required for NVMe, GPU or high-TDP CPU setups RAID Controllers: HPE Smart Array P408i-a SR (Gen10) and other Gen10 tri mode controllers	Power Supplies: Dual hot plug redundant PSUs ranging from 750 W to 1800 W (Platinum/Titanium, AC or DC options) Cooling: Air cooled with up to six hot swap fans and N+1 redundancy
Operating System Support	Microsoft Windows Server 2016 / 2019 / 2022 Red Hat Enterprise Linux (RHEL) SUSE Linux Enterprise Server (SLES) VMware ESXi (vSphere 6.7 U3, 7.x, 8.x) Additional: Ubuntu, Oracle Linux, Citrix XenServer	Microsoft Windows Server Red Hat Enterprise Linux SUSE Linux Enterprise Server VMware ESXi Canonical Ubuntu Server LTS
Security Features	iLO 5 Security: Server Configuration Lock, BIOS Advisor, iLO Security Dashboard Secure Boot & Secure Erase: Supported via system firmware TPM 2.0 Support: Optional module available	Lenovo XClarity Controller with Platform Firmware Resiliency (PFR) Embedded TPM 2.0 (FIPS/CC TCG certified) Optional lockable bezel and chassis intrusion detection
Management & Monitoring	Integrated Lights Out (iLO 5): Remote management, firmware control, health alerts Management Tools: HPE Intelligent Provisioning, InfoSight, OneView Standard APIs: Redfish, RESTful API, SNMP v3, IPMI 2.0	Lenovo XClarity Controller (XCC) with RESTful Redfish API Supports Lenovo XClarity Administrator, Energy Manager, and integrations with VMware, Microsoft System Center
Warranty & Support	Standard Warranty: 3-Year Parts, 3-Year Labor, 3-Year Onsite (Next Business Day) Optional Services: HPE Pointnext Tech Care, Foundation Care, Proactive Care	Standard Warranty: 3 Years Warranty Support Options: Warranty extensions available via Lenovo service plans

Key Features Comparison

Powerful Performance for Diverse Workloads:

Equipped with Intel® Xeon® Scalable processors, the DL380 Gen10 delivers reliable, high-performance processing for various business applications.

Versatile Storage Options:

Supports a range of storage configurations, from SATA and SAS to ultra-fast NVMe drives, providing flexibility to match your data needs and business growth.

Advanced Security Features

Incorporates HPE’s Silicon Root of Trust technology, offering a secure boot and robust protection against unauthorized firmware changes.

Scalable Architecture and Expansion Flexibility:

With PCIe slots, the DL380 Gen10 offers enhanced flexibility, allowing easy expansion for evolving IT infrastructure and workload demands.

Energy Efficient Design:

Designed to reduce power consumption while maintaining high performance, helping lower operational costs and supporting eco-friendly objectives.

Reliable Redundancy and Fault Tolerance:

Dual power supplies and redundant fans maximize uptime, ensuring continuous operation in mission-critical environments.

High Processing Power

Equipped with Intel Xeon Scalable processors (up to 3rd Gen), the SR650 V2 delivers exceptional performance for demanding applications

Massive Storage Capacity

With support for up to 40 drives, the server offers extensive storage options, providing flexibility for large data volumes

Enhanced Memory Capacity

Featuring up to 8TB of DDR4 memory, the SR650 V2 allows for seamless multitasking and efficient processing of complex applications

Energy Efficiency

Built to reduce power consumption, Lenovo’s energy-efficient architecture helps minimize operational costs while delivering high performance

Advanced Virtualization Capabilities

Designed to support virtualized workloads, the SR650 V2 helps enterprises maximize their infrastructure efficiency and manage multiple virtual machines

Flexible Networking Options

With support for multiple networking configurations, including 10/25 GbE, the SR650 V2 enables high-speed connectivity and robust network performance

HPE ProLiant DL380 Gen10 Server vs Lenovo ThinkSystem SR650 V2 Server : Which should I choose?

Choosing the right server is a critical decision for any business, and comparing HPE ProLiant DL380 Gen10 Server and Lenovo ThinkSystem SR650 V2 Server gives you clear insights into which solution aligns best with your IT requirements. These servers are built for high performance, but they may differ in areas such as processor capacity, memory, storage, and scalability, making a side-by-side comparison easy.

This direct comparison helps you quickly identify the strengths and limitations of each server, which helps you determine which model best supports your workloads, applications, and long-term IT goals. By evaluating them together, you can make a smarter investment that ensures reliability and efficiency for your business.

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