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Quick Comparison of HPE ProLiant DL380 Gen10 Server vs Dell PowerEdge R350 Rack Server at a Glance

The server comparison table provides a quick overview of the key specifications and key features for HPE ProLiant DL380 Gen10 Server and Dell PowerEdge R350 Rack Server Let’s take a look at the comparison table below.

Features
HPE ProLiant DL380 Gen10 Server

HPE ProLiant DL380 Gen10 Server

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Dell PowerEdge R350 Rack Server

Dell PowerEdge R350 Rack Server

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Server Type / Form Factor

  • Type: Rack Server

  • Form Factor: 2U Rackmount

  • Socket: Dual socket (supports up to 2 processors)

  • Type: Rack Server

  • Form Factor: 1U Rackmount

  • Socket: Single socket (Intel Xeon E 2300 series or Pentium up to 8 cores)
Processor (CPU)

  • Processor Family: Intel Xeon Scalable Processors (1st and 2nd Gen)

  • Supported Cores: 4 to 28 cores per CPU (e.g. Bronze 3200, Silver 4200, Gold 5200/6200 series)

  • Base Frequency: ~1.9 GHz to ~3.2 GHz depending on model

  • Max TDP: ~85 W to ~205 W per processor

  • Memory per Socket: Up to 1 TB (Silver/Gold) or up to 4.5 TB per socket (Large memory tiers with Optane)

  • Supported CPUs: One Intel Xeon E 2300 series processor (up to 8 cores)

  • Also supports: Intel Pentium processors (up to 2 cores)
Memory (RAM)

  • Type: DDR4 HPE SmartMemory (RDIMM, LRDIMM, DC Persistent Memory)

  • DIMM Slots: 24 slots (12 per processor, 6 channels each)

  • Max Capacity:

    • Up to 2.0 TB using RDIMM @ 2933 MT/s

    • Up to 3.0 TB using LRDIMM @ 2933 or 3200 MT/s

    • Up to 4.5 TB per socket using Intel Optane Persistent Memory (select SKUs)

  • Memory Type: ECC UDIMM DDR4

  • DIMM Slots: 4 slots total

  • Max Capacity: Up to 128 GB

  • Speed: Up to 3200 MT/s (2666 MT/s for Pentium)
Storage

  • Front Drive Bays: Flexible chassis options:

    • Up to 12 × LFF (3.5") SAS/SATA HDD/SSD

    • Or up to 24 × SFF (2.5") SAS/SATA/NVMe



  • Optional Rear/Mid-Tray: Additional 2–6 SFF or LFF drives

  • Supported Drive Types: SAS, SATA, NVMe U.2/U.3 via tri mode Smart Array controllers

  • Boot Options: Optional M.2 SATA boot module

  • Drive Bay Options:

    • Up to 4 × 3.5 SAS/SATA hot swap HDD/SSD

    • Up to 8 × 2.5 SAS/SATA hot swap HDD/SSD



  • Controllers: PERC H345, H345f, H355, H355f, H755, H755f; HBA355i/f; External HBA355e; SW/HW RAID with PERC 10.5/11
Expansion / Connectivity

  • PCIe Slots: Up to 8–9 × PCIe 3.0 slots depending on riser configuration

  • Networking: OCP 3.0 mezzanine slot available (for 10/25/100 GbE modules)

  • PCIe Slots: Up to three PCIe Gen 4 expansion slots (config dependent)

  • Networking: Embedded dual 1 GbE LOM (Broadcom BCM5720)
Redundancy & Reliability

  • Power Supplies: Redundant Flex Slot power supplies (e.g., 800 W, 1600 W Platinum)

  • Cooling: Hot-plug fans; high-performance kit required for NVMe, GPU or high-TDP CPU setups

  • RAID Controllers: HPE Smart Array P408i-a SR (Gen10) and other Gen10 tri mode controllers

  • Power Supplies: Two redundant hot plug AC or DC PSUs available

  • Cooling: Air cooled with hot plug fans
Operating System Support

  • Microsoft Windows Server 2016 / 2019 / 2022

  • Red Hat Enterprise Linux (RHEL)

  • SUSE Linux Enterprise Server (SLES)

  • VMware ESXi (vSphere 6.7 U3, 7.x, 8.x)

  • Additional: Ubuntu, Oracle Linux, Citrix XenServer

  • Microsoft Windows Server with Hyper V

  • Red Hat Enterprise Linux

  • SUSE Linux Enterprise Server

  • VMware ESXi

  • Canonical Ubuntu Server LTS
Security Features

  • iLO 5 Security: Server Configuration Lock, BIOS Advisor, iLO Security Dashboard

  • Secure Boot & Secure Erase: Supported via system firmware

  • TPM 2.0 Support: Optional module available

  • Cryptographically signed firmware and Silicon Root of Trust

  • Secure Boot, System Erase, System Lockdown (iDRAC9 Enterprise required)

  • TPM 2.0 (FIPS, CC TCG certified)
Management & Monitoring

  • Integrated Lights Out (iLO 5): Remote management, firmware control, health alerts

  • Management Tools: HPE Intelligent Provisioning, InfoSight, OneView Standard

  • APIs: Redfish, RESTful API, SNMP v3, IPMI 2.0

  • iDRAC9 with Lifecycle Controller; iDRAC Direct USB port

  • RESTful Redfish API; Dell OpenManage Enterprise integration
Warranty & Support

  • Standard Warranty: 3-Year Parts, 3-Year Labor, 3-Year Onsite (Next Business Day)

  • Optional Services: HPE Pointnext Tech Care, Foundation Care, Proactive Care

  • Standard Warranty: 3 Year Dell Basic Hardware Warranty with Next Business Day Onsite Service

  • Optional Extended Support: Dell ProSupport or ProSupport Plus available beyond 3 years

Key Features Comparison

Powerful Performance for Diverse Workloads:
Equipped with Intel® Xeon® Scalable processors, the DL380 Gen10 delivers reliable, high-performance processing for various business applications.
Versatile Storage Options:
Supports a range of storage configurations, from SATA and SAS to ultra-fast NVMe drives, providing flexibility to match your data needs and business growth.
Advanced Security Features
Incorporates HPE’s Silicon Root of Trust technology, offering a secure boot and robust protection against unauthorized firmware changes.
Scalable Architecture and Expansion Flexibility:
With PCIe slots, the DL380 Gen10 offers enhanced flexibility, allowing easy expansion for evolving IT infrastructure and workload demands.
Energy Efficient Design:
Designed to reduce power consumption while maintaining high performance, helping lower operational costs and supporting eco-friendly objectives.
Reliable Redundancy and Fault Tolerance:
Dual power supplies and redundant fans maximize uptime, ensuring continuous operation in mission-critical environments.
Powerful Processing
Equipped with Intel Xeon E-2300 Series Processors with up to 8 cores per processor. Delivers robust performance across various workloads, ensuring efficient operations and improved business productivity.
Expandable Memory
Supports up to 64GB DDR4 memory. Provides fast data access and enhanced application performance, enabling smooth multitasking and handling of demanding applications.
Flexible Storage Options
Configurable with NVMe SSDs and SAS/SATA HDDs. Offers customizable storage solutions to meet diverse needs, ensuring high-speed data retrieval and increased storage capacity for large datasets
Advanced Network Capabilities
Integrated 1GbE ports with an optional upgrade to 10GbE. Ensures fast network connectivity and enhanced data transfer rates, improving overall network performance and reducing bottlenecks.
Efficient Management
Dell iDRAC9 with Lifecycle Controller. Simplifies server management with advanced remote capabilities, reducing on-site management needs and freeing up IT resources for other critical tasks.
Enhanced Security
Includes Secure Boot and System Lockdown. Protects your data and applications against unauthorized access and cyber threats, ensuring business continuity and data integrity.

HPE ProLiant DL380 Gen10 Server vs Dell PowerEdge R350 Rack Server : Which should I choose?

Choosing the right server is a critical decision for any business, and comparing HPE ProLiant DL380 Gen10 Server and Dell PowerEdge R350 Rack Server gives you clear insights into which solution aligns best with your IT requirements. These servers are built for high performance, but they may differ in areas such as processor capacity, memory, storage, and scalability, making a side-by-side comparison easy.

This direct comparison helps you quickly identify the strengths and limitations of each server, which helps you determine which model best supports your workloads, applications, and long-term IT goals. By evaluating them together, you can make a smarter investment that ensures reliability and efficiency for your business.

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