Quick Comparison of Dell PowerEdge R750xs Rack Server vs HPE ProLiant DL380 Gen10 Plus Server at a Glance

The server comparison table provides a quick overview of the key specifications and key features for Dell PowerEdge R750xs Rack Server and HPE ProLiant DL380 Gen10 Plus Server Let’s take a look at the comparison table below.

Features	Dell PowerEdge R750xs Rack Server View Check the Price	HPE ProLiant DL380 Gen10 Plus Server View Check the Price
Server Type / Form Factor	Type: Rack Server Form Factor: 2U Rackmount Socket: Dual socket (supports up to 3rd Generation Intel Xeon Scalable, up to 32 cores/socket)	Type: Rack Server Form Factor: 2U Rackmount Socket: Dual socket (supports up to 2 processors)
Processor (CPU)	Supported CPUs: Up to two 3rd Generation Intel Xeon Scalable processors (up to 32 cores per socket) Max TDP: ~220 W per processor	Processor Family: 3rd Generation Intel Xeon Scalable Processors Supported Cores: 8 to 60 cores per CPU (e.g. Xeon Gold 6326, 6330N, 8352, 8380) Base Frequency: ~2.1 GHz to ~3.6 GHz depending on model Max TDP: ~105 W to 270 W per processor
Memory (RAM)	Memory Type: DDR4 Registered ECC (RDIMM) DIMM Slots: 16 slots total (8 per CPU) Max Capacity: Up to 1 TB Speed: Up to 3200 MT/s	Type: DDR4 HPE SmartMemory (RDIMM/LRDIMM and Intel Optane Persistent Memory) DIMM Slots: 32 (16 per processor) Max Capacity: Up to 8.1 TB using RDIMM/LRDIMM, or up to 11.2 TB with Intel Optane Persistent Memory Speed: Up to 3200 MT/s (depending on CPU and memory type)
Storage	Drive Bay Options: Up to 8 × 3.5 SAS/SATA Up to 12 × 3.5 SAS/SATA Up to 8 × 2.5 SAS/SATA/NVMe Up to 16 × 2.5 SAS/SATA + 8 × NVMe Rear Bays: Up to 2 × 2.5 SAS/SATA/NVMe Controllers: PERC H345, H355, H745, H755, H755N; HBA355i; S150; Boot: BOSSS1 dual M.2; External: PERC H840	Front Drive Bays: Multiple chassis options: 8SFF standard (expandable to 24SFF) 8LFF standard (expandable to 12LFF) Rear/Mid Tray Options: Optional 6SFF rear, 8SFF mid tray, LFF mid tray Supported Drive Types: SAS, SATA, NVMe (U.2/U.3 with tri-mode controllers) M.2 Boot: Optional M.2 SATA boot or NVMe boot support
Expansion / Connectivity	PCIe Slots: Up to 5 PCIe Gen 4 + 1 Gen 3 riser slots (depending on configuration) Networking: Embedded dual 1 GbE LOM; optional OCP 3.0 mezzanine card	PCIe Slots: Up to 9 expansion slots (PCIe Gen4) depending on riser configuration OCP Networking: 1× OCP 3.0 x16 mezzanine slot (flexible networking/storage)
Redundancy & Reliability	Power Supplies: Hot plug redundant PSUs: 600 W, 800 W, 1100 W, 1400 W (Titanium/Platinum AC or DC options) Cooling: Up to 6 hot swap fans; standard or high performance fan configurations	Power Supplies: Redundant hot-plug Flex Slot Platinum power (e.g., 800W) Cooling: Standard fans; high performance fan option required for NVMe or GPU configs
Operating System Support	Microsoft Windows Server with Hyper V Red Hat Enterprise Linux SUSE Linux Enterprise Server VMware ESXi / vSAN Canonical Ubuntu Server LTS	Microsoft Windows Server 2019 / 2022 Red Hat Enterprise Linux (RHEL) SUSE Linux Enterprise Server (SLES) VMware ESXi (7.x / 8.x) Other: Ubuntu, Oracle Linux, Citrix XenServer
Security Features	Cryptographically signed firmware; Silicon Root of Trust Secure Boot, Secure Erase, System Lockdown (requires iDRAC9 Enterprise/Datacenter) TPM 2.0 (FIPS/CC TCG certified)	Silicon Root of Trust: Secures firmware and processor identity at ROM-level Secure Boot & Erase: Ensures verified, tamper resistant system startup and clean decommission iLO 5 Security Enhancements: Server Configuration Lock, iLO Security Dashboard, BIOS advisor
Management & Monitoring	iDRAC9 with Lifecycle Controller; iDRAC Direct USB port; RESTful Redfish API; iDRAC Service Module Tools: Dell OpenManage Enterprise, CloudIQ; integrations with VMware, Microsoft System Center; Ansible, Terraform support	iLO 5: Embedded management for remote control, firmware updates, monitoring Tools: HPE InfoSight (predictive analytics), OneView, Intelligent Provisioning APIs: Redfish, RESTful, SNMP v3, IPMI 2.0
Warranty & Support	Standard Warranty: 3 Year Dell Basic Hardware Warranty with Next Business Day Onsite Service Optional Extended Support: Dell ProSupport or ProSupport Plus available beyond 3 years	Standard Warranty: 3 Years Parts, 3 Years Labor, 3 Years Onsite (Next Business Day) Optional Services: HPE Pointnext Tech Care, Foundation Care, Proactive Care

Key Features Comparison

Powerful Performance

Powered by the latest Intel Xeon Scalable Processors, the Dell PowerEdge R750xs ensures high-speed performance for demanding applications, handling large datasets and complex tasks with ease

Flexible Storage Options

The R750xs supports a variety of storage configurations, including NVMe, SAS, and SATA drives, allowing you to scale your storage capacity based on your growing business needs.

Enhanced Cooling Efficiency

Featuring multi-vector cooling technology, the R750xs optimizes airflow to maintain efficient thermal management, reducing the risk of overheating and lowering energy consumption.

High Memory Capacity

With support for up to 16 DIMMs and DDR4 or DDR5 memory, the R750xs can handle large-scale data processing, virtualization, and high-performance computing.

Redundant Power Supplies

Equipped with dual hot-plug redundant power supplies, the R750xs ensures continuous uptime, minimizing the risk of system failures during critical operations.

High Performance for Intensive Workloads

Powered by 3rd Gen Intel® Xeon® Scalable Processors, the DL380 Gen10 Plus delivers exceptional performance, making it ideal for data-intensive applications.

Scalable Storage Solutions

Offers flexible storage options, from SATA and SAS HDDs to high-speed NVMe SSDs, providing businesses with the storage configurations they need.

Advanced Security Features

Built with HPE Silicon Root of Trust, a robust security framework that ensures secure boot and protects against unauthorized firmware modifications.

Flexible Expansion and Connectivity

The DL380 Gen10 Plus supports PCIe Gen4, enabling high-speed expansion for enhanced networking and storage capabilities.

Energy Efficient

Designed for lower power consumption without sacrificing performance, reducing operational costs and supporting eco-friendly initiatives.

Redundant Power Supplies and Cooling

Ensures reliability with dual power supplies and optimized cooling, minimizing downtime and maximizing productivity.

Dell PowerEdge R750xs Rack Server vs HPE ProLiant DL380 Gen10 Plus Server : Which should I choose?

Choosing the right server is a critical decision for any business, and comparing Dell PowerEdge R750xs Rack Server and HPE ProLiant DL380 Gen10 Plus Server gives you clear insights into which solution aligns best with your IT requirements. These servers are built for high performance, but they may differ in areas such as processor capacity, memory, storage, and scalability, making a side-by-side comparison easy.

This direct comparison helps you quickly identify the strengths and limitations of each server, which helps you determine which model best supports your workloads, applications, and long-term IT goals. By evaluating them together, you can make a smarter investment that ensures reliability and efficiency for your business.

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